Difference between revisions of "Model Overview"
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|<math>38.3-4.46 \cdot 10^{6}</math> | |<math>38.3-4.46 \cdot 10^{6}</math> | ||
|<math> min^{-1} </math> | |<math> min^{-1} </math> | ||
− | | | + | |1879.7 |
− | | | + | |23.13 |
|9.9423 | |9.9423 | ||
|1.5503 | |1.5503 | ||
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|<math>0.0011-10400</math> | |<math>0.0011-10400</math> | ||
|<math> nM </math> | |<math> nM </math> | ||
− | | | + | |1.58 |
− | | | + | |730.63 |
|5.9389 | |5.9389 | ||
|2.3412 | |2.3412 | ||
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|0.144-51.2 | |0.144-51.2 | ||
|<math> min^{-1} </math> | |<math> min^{-1} </math> | ||
− | | | + | |1.1997 |
− | | | + | |21.7 |
|2.5303 | |2.5303 | ||
|1.5324 | |1.5324 |
Revision as of 12:53, 24 November 2017
Contents
List of Model Reactions
*1 Reactions taking place only in the scenario which includes the activating complex
*2 Reactions taking place only in the scenario which includes the antisense RNA interactions
Reactions |
---|
*1
*1 *1 *1 *1 *1
*1 *2
*1 *2
|
Parameters for model reactions
Reaction | Parameter | Value | Units | Mode | Spread | Location
parameter (μ) |
Scale
parameter (σ) |
---|---|---|---|---|---|---|---|
Binding of R2 to OR operator | 0.005−5.8 | 0.299 | 6.8 | 0.15471 | 1.1661 | ||
0.09−0.846 | 0.489 | 1.98 | −0.37642 | 0.58225 | |||
Binding of R2 to OA operator | 0.005−5.8 | 0.299 | 6.8 | 0.15471 | 1.1661 | ||
0.09−0.846 | 0.489 | 1.98 | −0.37642 | 0.58225 | |||
Binding of R2 to A | 10.02 | 13.192 | 1.2977 | ||||
1879.7 | 23.13 | 9.9423 | 1.5503 | ||||
Binding of R2 to C | 1.58 | 730.63 | 5.9389 | 2.3412 | |||
0.816 | 244 | 4.2872 | 2.119 | ||||
Binding of A-R2 to OA' operator | 0.005−5.8 | 0.299 | 6.8 | 0.15471 | 1.1661 | ||
0.09−0.846 | 0.489 | 1.98 | −0.37642 | 0.58225 | |||
Synthesis of C | 0.00315−85.5 | 0.094 | 60.49 | 0.87914 | 1.8017 | ||
Transcription of r | 0.16−8.24 | 0.8346 | 3.55 | 0.63056 | 0.90076 | ||
18.2−33 | 20.7 | 1.34 | 3.1107 | 0.28276 | |||
0.0518-14.5 | 0.867 | 4.09 | 0.78694 | 0.96428 | |||
Transcription of a | 0.001−0.2 | 0.0037 | 10.93 | −3.8324 | 1.3259 | ||
0.11−5.65 | 0.572 | 3.5 | 0.2514 | 0.89956 | |||
0.039-8.82 | 0.587 | 3.875 | 0.35255 | 0.94054 | |||
Antisense interaction between r and a | 0.4−89 | 7.8 | 7.27 | 3.4665 | 1.1882 | ||
0.006−6 | 0.223 | 4.8 | −0.43359 | 1.0326 | |||
Translation of R | 0.165−5.86 | 0.744 | 3.2 | 0.42952 | 0.85176 | ||
Translation of A | 0.11−4 | 0.5 | 3.2 | 0.053356 | 0.85327 | ||
Formation of homo-dimer R2 | 2.58-42.9 | 3.89 | 1.9 | 1.6716 | 0.55779 | ||
0.144-51.2 | 1.1997 | 21.7 | 2.5303 | 1.5324 | |||
Degradation of r | 0.03−0.365 | 0.14 | 2.06 | −1.5916 | 0.60824 | ||
Degradation of R | 1.78 | −6.2837 | 0.50981 | ||||
Degradation of R2 | 1.78 | −6.2837 | 0.50981 | ||||
Degradation of a | 0.03−0.365 | 0.14 | 2.06 | −1.5916 | 0.60824 | ||
Degradation of A | 1.78 | −6.2837 | 0.50981 | ||||
Degradation of C | 5.1 | −4.6234 | 1.0539 | ||||
Degradation of C2-R2 | 1.78 | −6.2837 | 0.50981 | ||||
Degradation of A-R2 | 1.78 | −6.2837 | 0.50981 | ||||
Degradation of r-a | 0.35−69.3 | 4.9 | 14.1 | 2.5669 | 0.98835 | ||
Diffusion of C and Ce | 0.1−24 | 2.8 | 4.27 | 1.9947 | 0.98233 | ||
Degradation of Ce | 5.1 | −4.6234 | 1.0539 | ||||
Cellular growth | Failed to parse (PNG conversion failed; check for correct installation of latex and dvipng (or dvips + gs + convert)): μ | 0.0004−0.0107 | 0.0022 | 7.5 | −5.4517 | 0.80808 |
Parameters for cell colony growth
Parameter | Value | Units |
---|---|---|
Failed to parse (PNG conversion failed; check for correct installation of latex and dvipng (or dvips + gs + convert)): τ | ||
Failed to parse (PNG conversion failed; check for correct installation of latex and dvipng (or dvips + gs + convert)): λ | ||
Initial concentrations of species
Species | Initial concentration | Units | Compartment |
---|---|---|---|
OR | 0.9592 | Cell | |
OA | 0.9592 | Cell | |
OR-R2 | 0 | Cell | |
OA-R2 | 0 | Cell | |
OA'-AR2 | 0 | Cell | |
r | 0 | Cell | |
a | 0 | Cell | |
r-a | 0 | Cell | |
R | 0 | Cell | |
R2 | 0 | Cell | |
A | 0 | Cell | |
C | 0 | Cell | |
AR2 | 0 | Cell | |
C2R2 | 0 | Cell | |
Ce | 0 | Environment |