Model Overview

Parameters for model reactions

Reaction	Parameter	Value	Units	Distribution Mode	Confidence Interval	Location parameter (μ)	Scale parameter (σ)
Binding of R2 to OR operator	$K_{d1}$		$nM$
	$k^{-}_{1}$		$min^{-1}$
Binding of R2 to OA operator	$K_{d2}$		$nM$
	$k^{-}_{2}$		$min^{-1}$
Binding of R2 to A	$K_{d3}$		$nM$
	$k^{-}_{3}$		$min^{-1}$
Binding of R2 to C	$K_{d4}$		$nM$
	$k^{-}_{4}$		$min^{-1}$
Binding of AR2 to OA' operator	$K_{d5}$		$nM$
	$k^{-}_{5}$		$min^{-1}$
Synthesis of C	$K_{C}$		$min^{-1}$
Transcription of r	Failed to parse (Cannot store math image on filesystem.): K_{R}		$min^{-1}$
Transcription of a	Failed to parse (Cannot store math image on filesystem.): K_{A}		$min^{-1}$
Antisense interaction between r and a	$K_{ar}$		$min^{-1}$
Translation of R	$P_{R}$		$min^{-1}$
Translation of A	$P_{A}$		$min^{-1}$
Formation of homo-dimer R2
Degradation of r	$d_{mR}$		$min^{-1}$
Degradation of R2	$d_{R}$		$min^{-1}$
Degradation of a	$d_{mA}$		$min^{-1}$
Degradation of A	$d_{A}$		$min^{-1}$
Degradation of C	$d_{C}$		$min^{-1}$
Degradation of C2-R2	$d_{CR}$		$min^{-1}$
Degradation of A-R2	$d_{AR}$		$min^{-1}$
Degradation of r-a	$d_{mAR}$		$min^{-1}$
Diffusion of C and Ce	$D$		$min^{-1}$
Degradation of Ce	$d_{C}$		$min^{-1}$
Cellular growth	Failed to parse (PNG conversion failed; check for correct installation of latex and dvipng (or dvips + gs + convert)): μ		$min^{-1}$

Parameters for cell colony growth

Parameter	Value	Units
Failed to parse (PNG conversion failed; check for correct installation of latex and dvipng (or dvips + gs + convert)): τ	Failed to parse (Cannot store math image on filesystem.): 58-165	$min$
Failed to parse (PNG conversion failed; check for correct installation of latex and dvipng (or dvips + gs + convert)): λ	$0.8$	$-$
$V_{0}$	$1.2$	$μm^{3}$
$V_{tot}$	$2 \cdot 10^{−4}$	$μl$