Difference between revisions of "Overview of Parameters"

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(Overview of Enzyme Parameters)
(Overview of Enzyme Parameters)
 
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== Overview of Parameters ==
 
  
  
 
== Overview of Reaction Parameters ==
 
== Overview of Reaction Parameters ==
 +
 +
{|class="wikitable"
 +
<table border='1' style="text-align:center">
 +
! Reaction
 +
! Enzyme
 +
! E.C.
 +
! Parameter
 +
! Value
 +
! Unit
 +
! Species
 +
|-
 +
|[[Transformation of FA to AA |Transformation of FA to AA]]
 +
|PLA2
 +
|3.1.1.4
 +
|<math>K</math>
 +
|X
 +
|<math> μM </math>
 +
|Y
 +
|-
 +
|[[Transformation of AA to PGH2 |Transformation of AA to PGH2]]
 +
|COX-2
 +
|1.14.99.1
 +
|<math>K</math>
 +
|X
 +
|<math> μM </math>
 +
|Y
 +
|-
 +
|[[Transformation of PGH2 to PGF2α |Transformation of PGH2 to PGF2α]]
 +
|PGFS
 +
|1.1.1.188
 +
|<math>K</math>
 +
|X
 +
|<math> nM </math>
 +
|Y
 +
|-
 +
|[[Transformation of PGH2 to TXA2  |Transformation of PGH2 to TXA2]]
 +
|TXAS
 +
|5.3.99.5
 +
|<math>K</math>
 +
|X
 +
|<math> nM </math>
 +
|Y
 +
|-
 +
|[[Transformation of PGH2 to PGI2 |Transformation of PGH2 to PGI2]]
 +
|PGIS
 +
|5.3.99.4
 +
|<math>K</math>
 +
|X
 +
|<math> nM </math>
 +
|Y
 +
|-
 +
|[[Transformation of PGH2 to PGD2 |Transformation of PGH2 to PGD2]]
 +
|PGDS
 +
|5.3.99.2
 +
|<math>K</math>
 +
|X
 +
|<math> nM </math>
 +
|Y
 +
|-
 +
|[[Transformation of PGH2 to PGE2 |Transformation of PGH2 to PGE2]]
 +
|PGES
 +
|5.3.99.3
 +
|<math>K</math>
 +
|X
 +
|<math> nM </math>
 +
|Y
 +
|-
 +
|[[Transformation of TXA2 to TXB2 |Transformation of TXA2 to TXB2]]
 +
|
 +
|
 +
|<math>K</math>
 +
|X
 +
|<math> nM </math>
 +
|Y
 +
|-
 +
|[[Transformation of PGI2 to 6-K-PGF1α |Transformation of PGI2 to 6-K-PGF1α]]
 +
|
 +
|
 +
|<math>K</math>
 +
|X
 +
|<math> nM </math>
 +
|Y
 +
|-
 +
|[[Transformation of PGD2 to PGJ2 |Transformation of PGD2 to PGJ2]]
 +
|
 +
|
 +
|<math>K</math>
 +
|X
 +
|<math> nM </math>
 +
|Y
 +
|-
 +
|[[Transformation of PGJ2 to 15-D-PGJ2 |Transformation of PGJ2 to 15-D-PGJ2]]
 +
|
 +
|
 +
|<math>K</math>
 +
|X
 +
|<math> nM </math>
 +
|Y
 +
|}
  
 
== Overview of Enzyme Parameters ==
 
== Overview of Enzyme Parameters ==
 +
 +
A collection of literature parameters related to the model can be found [[Literature Parameters|'''here''']].
  
 
{|class="wikitable"
 
{|class="wikitable"
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! Unit
 
! Unit
 
! Species
 
! Species
 +
! Reference
 +
|-
 +
|rowspan="2" | [[Transformation of FA to AA |Transformation of FA to AA]]
 +
|rowspan="2" | PLA2
 +
|rowspan="2" | 3.1.1.4
 +
|<math>Km</math>
 +
|X
 +
|<math> μM </math>
 +
|rowspan="2" |Y
 +
|rowspan="2" |A
 +
|-
 +
|<math>Kcat</math>
 +
|Z
 +
|<math> min^{-1} </math>
 
|-
 
|-
 
|rowspan="2" | [[Transformation of AA to PGH2 |Transformation of AA to PGH2]]  
 
|rowspan="2" | [[Transformation of AA to PGH2 |Transformation of AA to PGH2]]  
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|rowspan="2" | 1.14.99.1
 
|rowspan="2" | 1.14.99.1
 
|<math>Km</math>  
 
|<math>Km</math>  
|33
+
|X
 
|<math> μM </math>
 
|<math> μM </math>
|rowspan="2" |PMN
+
|rowspan="2" |Y
 +
|rowspan="2" |A
 
|-
 
|-
 
|<math>Kcat</math>  
 
|<math>Kcat</math>  
|1000
+
|Z
 
|<math> min^{-1} </math>
 
|<math> min^{-1} </math>
 
|-
 
|-
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|<math>Km</math>  
 
|<math>Km</math>  
 
|X
 
|X
|<math> nM </math>
+
|<math> μM </math>
 
|rowspan="2" |Y
 
|rowspan="2" |Y
 +
|rowspan="2" |A
 
|-
 
|-
 
|<math>Kcat</math>  
 
|<math>Kcat</math>  
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|<math>Km</math>  
 
|<math>Km</math>  
 
|X
 
|X
|<math> nM </math>
+
|<math> μM </math>
 
|rowspan="2" |Y
 
|rowspan="2" |Y
 +
|rowspan="2" |A
 
|-
 
|-
 
|<math>Kcat</math>  
 
|<math>Kcat</math>  
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|<math>Km</math>  
 
|<math>Km</math>  
 
|X
 
|X
|<math> nM </math>
+
|<math> μM </math>
 
|rowspan="2" |Y
 
|rowspan="2" |Y
 +
|rowspan="2" |A
 
|-
 
|-
 
|<math>Kcat</math>  
 
|<math>Kcat</math>  
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|<math> nM </math>
 
|<math> nM </math>
 
|rowspan="2" |Y
 
|rowspan="2" |Y
 +
|rowspan="2" |A
 
|-
 
|-
 
|<math>Kcat</math>  
 
|<math>Kcat</math>  
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|<math> nM </math>
 
|<math> nM </math>
 
|rowspan="2" |Y
 
|rowspan="2" |Y
 +
|rowspan="2" |A
 
|-
 
|-
 
|<math>Kcat</math>  
 
|<math>Kcat</math>  
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|<math> min^{-1} </math>
 
|<math> min^{-1} </math>
 
|}
 
|}
 +
 +
== Overview of Feedback Parameters ==
 +
 +
{|class="wikitable"
 +
<table border='1' style="text-align:center">
 +
! Feedback
 +
! Parameter
 +
! Value
 +
! Unit
 +
! Species
 +
|-
 +
|
 +
|<math>Ki</math>
 +
|X
 +
|<math> μM </math>
 +
|Y
 +
|}
 +
 +
== Overview of Product Inhibition Parameters ==
 +
 +
{|class="wikitable"
 +
<table border='1' style="text-align:center">
 +
! Species
 +
! Parameter
 +
! Value
 +
! Unit
 +
! Species
 +
|-
 +
|
 +
|<math>Ki</math>
 +
|X
 +
|<math> μM </math>
 +
|Y
 +
|}
 +
 +
== Overview of Decay Parameters ==
 +
 +
{|class="wikitable"
 +
<table border='1' style="text-align:center">
 +
! Species
 +
! Parameter
 +
! Value
 +
! Unit
 +
! Species
 +
|-
 +
|
 +
|<math>Kd</math>
 +
|X
 +
|<math> μM </math>
 +
|Y
 +
|}
 +
 +
== Models ==
 +
 +
Insert models for keratinocytes and fibroblasts here
 +
 +
== References ==
 +
<references/>

Latest revision as of 16:50, 4 February 2016


Overview of Reaction Parameters

Reaction Enzyme E.C. Parameter Value Unit Species
Transformation of FA to AA PLA2 3.1.1.4 K X Failed to parse (Cannot store math image on filesystem.): μM Y
Transformation of AA to PGH2 COX-2 1.14.99.1 K X Failed to parse (Cannot store math image on filesystem.): μM Y
Transformation of PGH2 to PGF2α PGFS 1.1.1.188 K X  nM Y
Transformation of PGH2 to TXA2 TXAS 5.3.99.5 K X  nM Y
Transformation of PGH2 to PGI2 PGIS 5.3.99.4 K X  nM Y
Transformation of PGH2 to PGD2 PGDS 5.3.99.2 K X  nM Y
Transformation of PGH2 to PGE2 PGES 5.3.99.3 K X  nM Y
Transformation of TXA2 to TXB2 K X  nM Y
Transformation of PGI2 to 6-K-PGF1α K X  nM Y
Transformation of PGD2 to PGJ2 K X  nM Y
Transformation of PGJ2 to 15-D-PGJ2 K X  nM Y

Overview of Enzyme Parameters

A collection of literature parameters related to the model can be found here.

Reaction Enzyme E.C. Parameter Value Unit Species Reference
Transformation of FA to AA PLA2 3.1.1.4 Failed to parse (Cannot store math image on filesystem.): Km X Failed to parse (Cannot store math image on filesystem.): μM Y A
Failed to parse (Cannot store math image on filesystem.): Kcat Z  min^{-1}
Transformation of AA to PGH2 COX-2 1.14.99.1 Failed to parse (Cannot store math image on filesystem.): Km X Failed to parse (Cannot store math image on filesystem.): μM Y A
Failed to parse (Cannot store math image on filesystem.): Kcat Z  min^{-1}
Transformation of PGH2 to PGF2α PGFS 1.1.1.188 Failed to parse (Cannot store math image on filesystem.): Km X Failed to parse (Cannot store math image on filesystem.): μM Y A
Failed to parse (Cannot store math image on filesystem.): Kcat Z  min^{-1}
Transformation of PGH2 to TXA2 TXAS 5.3.99.5 Failed to parse (Cannot store math image on filesystem.): Km X Failed to parse (Cannot store math image on filesystem.): μM Y A
Failed to parse (Cannot store math image on filesystem.): Kcat Z  min^{-1}
Transformation of PGH2 to PGI2 PGIS 5.3.99.4 Failed to parse (Cannot store math image on filesystem.): Km X Failed to parse (Cannot store math image on filesystem.): μM Y A
Failed to parse (Cannot store math image on filesystem.): Kcat Z  min^{-1}
Transformation of PGH2 to PGD2 PGDS 5.3.99.2 Failed to parse (Cannot store math image on filesystem.): Km X  nM Y A
Failed to parse (Cannot store math image on filesystem.): Kcat Z  min^{-1}
Transformation of PGH2 to PGE2 PGES 5.3.99.3 Failed to parse (Cannot store math image on filesystem.): Km X  nM Y A
Failed to parse (Cannot store math image on filesystem.): Kcat Z  min^{-1}

Overview of Feedback Parameters

Feedback Parameter Value Unit Species
Failed to parse (Cannot store math image on filesystem.): Ki X Failed to parse (Cannot store math image on filesystem.): μM Y

Overview of Product Inhibition Parameters

Species Parameter Value Unit Species
Failed to parse (Cannot store math image on filesystem.): Ki X Failed to parse (Cannot store math image on filesystem.): μM Y

Overview of Decay Parameters

Species Parameter Value Unit Species
Failed to parse (Cannot store math image on filesystem.): Kd X Failed to parse (Cannot store math image on filesystem.): μM Y

Models

Insert models for keratinocytes and fibroblasts here

References