Difference between revisions of "Overview of Parameters"
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+ | == Overview of Reaction Parameters == | ||
+ | |||
+ | {|class="wikitable" | ||
+ | <table border='1' style="text-align:center"> | ||
+ | ! Reaction | ||
+ | ! Enzyme | ||
+ | ! E.C. | ||
+ | ! Parameter | ||
+ | ! Value | ||
+ | ! Unit | ||
+ | ! Species | ||
+ | |- | ||
+ | |[[Transformation of FA to AA |Transformation of FA to AA]] | ||
+ | |PLA2 | ||
+ | |3.1.1.4 | ||
+ | |<math>K</math> | ||
+ | |X | ||
+ | |<math> μM </math> | ||
+ | |Y | ||
+ | |- | ||
+ | |[[Transformation of AA to PGH2 |Transformation of AA to PGH2]] | ||
+ | |COX-2 | ||
+ | |1.14.99.1 | ||
+ | |<math>K</math> | ||
+ | |X | ||
+ | |<math> μM </math> | ||
+ | |Y | ||
+ | |- | ||
+ | |[[Transformation of PGH2 to PGF2α |Transformation of PGH2 to PGF2α]] | ||
+ | |PGFS | ||
+ | |1.1.1.188 | ||
+ | |<math>K</math> | ||
+ | |X | ||
+ | |<math> nM </math> | ||
+ | |Y | ||
+ | |- | ||
+ | |[[Transformation of PGH2 to TXA2 |Transformation of PGH2 to TXA2]] | ||
+ | |TXAS | ||
+ | |5.3.99.5 | ||
+ | |<math>K</math> | ||
+ | |X | ||
+ | |<math> nM </math> | ||
+ | |Y | ||
+ | |- | ||
+ | |[[Transformation of PGH2 to PGI2 |Transformation of PGH2 to PGI2]] | ||
+ | |PGIS | ||
+ | |5.3.99.4 | ||
+ | |<math>K</math> | ||
+ | |X | ||
+ | |<math> nM </math> | ||
+ | |Y | ||
+ | |- | ||
+ | |[[Transformation of PGH2 to PGD2 |Transformation of PGH2 to PGD2]] | ||
+ | |PGDS | ||
+ | |5.3.99.2 | ||
+ | |<math>K</math> | ||
+ | |X | ||
+ | |<math> nM </math> | ||
+ | |Y | ||
+ | |- | ||
+ | |[[Transformation of PGH2 to PGE2 |Transformation of PGH2 to PGE2]] | ||
+ | |PGES | ||
+ | |5.3.99.3 | ||
+ | |<math>K</math> | ||
+ | |X | ||
+ | |<math> nM </math> | ||
+ | |Y | ||
+ | |- | ||
+ | |[[Transformation of TXA2 to TXB2 |Transformation of TXA2 to TXB2]] | ||
+ | | | ||
+ | | | ||
+ | |<math>K</math> | ||
+ | |X | ||
+ | |<math> nM </math> | ||
+ | |Y | ||
+ | |- | ||
+ | |[[Transformation of PGI2 to 6-K-PGF1α |Transformation of PGI2 to 6-K-PGF1α]] | ||
+ | | | ||
+ | | | ||
+ | |<math>K</math> | ||
+ | |X | ||
+ | |<math> nM </math> | ||
+ | |Y | ||
+ | |- | ||
+ | |[[Transformation of PGD2 to PGJ2 |Transformation of PGD2 to PGJ2]] | ||
+ | | | ||
+ | | | ||
+ | |<math>K</math> | ||
+ | |X | ||
+ | |<math> nM </math> | ||
+ | |Y | ||
+ | |- | ||
+ | |[[Transformation of PGJ2 to 15-D-PGJ2 |Transformation of PGJ2 to 15-D-PGJ2]] | ||
+ | | | ||
+ | | | ||
+ | |<math>K</math> | ||
+ | |X | ||
+ | |<math> nM </math> | ||
+ | |Y | ||
+ | |} | ||
+ | |||
+ | == Overview of Enzyme Parameters == | ||
+ | |||
+ | A collection of literature parameters related to the model can be found [[Literature Parameters|'''here''']]. | ||
{|class="wikitable" | {|class="wikitable" | ||
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! E.C. | ! E.C. | ||
! Parameter | ! Parameter | ||
+ | ! Value | ||
+ | ! Unit | ||
! Species | ! Species | ||
+ | ! Reference | ||
+ | |- | ||
+ | |rowspan="2" | [[Transformation of FA to AA |Transformation of FA to AA]] | ||
+ | |rowspan="2" | PLA2 | ||
+ | |rowspan="2" | 3.1.1.4 | ||
+ | |<math>Km</math> | ||
+ | |X | ||
+ | |<math> μM </math> | ||
+ | |rowspan="2" |Y | ||
+ | |rowspan="2" |A | ||
+ | |- | ||
+ | |<math>Kcat</math> | ||
+ | |Z | ||
+ | |<math> min^{-1} </math> | ||
+ | |- | ||
+ | |rowspan="2" | [[Transformation of AA to PGH2 |Transformation of AA to PGH2]] | ||
+ | |rowspan="2" | COX-2 | ||
+ | |rowspan="2" | 1.14.99.1 | ||
+ | |<math>Km</math> | ||
+ | |X | ||
+ | |<math> μM </math> | ||
+ | |rowspan="2" |Y | ||
+ | |rowspan="2" |A | ||
+ | |- | ||
+ | |<math>Kcat</math> | ||
+ | |Z | ||
+ | |<math> min^{-1} </math> | ||
+ | |- | ||
+ | |rowspan="2" | [[Transformation of PGH2 to PGF2α |Transformation of PGH2 to PGF2α]] | ||
+ | |rowspan="2" | PGFS | ||
+ | |rowspan="2" | 1.1.1.188 | ||
+ | |<math>Km</math> | ||
+ | |X | ||
+ | |<math> μM </math> | ||
+ | |rowspan="2" |Y | ||
+ | |rowspan="2" |A | ||
+ | |- | ||
+ | |<math>Kcat</math> | ||
+ | |Z | ||
+ | |<math> min^{-1} </math> | ||
+ | |- | ||
+ | |rowspan="2" | [[Transformation of PGH2 to TXA2 |Transformation of PGH2 to TXA2]] | ||
+ | |rowspan="2" | TXAS | ||
+ | |rowspan="2" | 5.3.99.5 | ||
+ | |<math>Km</math> | ||
+ | |X | ||
+ | |<math> μM </math> | ||
+ | |rowspan="2" |Y | ||
+ | |rowspan="2" |A | ||
+ | |- | ||
+ | |<math>Kcat</math> | ||
+ | |Z | ||
+ | |<math> min^{-1} </math> | ||
+ | |- | ||
+ | |rowspan="2" | [[Transformation of PGH2 to PGI2 |Transformation of PGH2 to PGI2]] | ||
+ | |rowspan="2" | PGIS | ||
+ | |rowspan="2" | 5.3.99.4 | ||
+ | |<math>Km</math> | ||
+ | |X | ||
+ | |<math> μM </math> | ||
+ | |rowspan="2" |Y | ||
+ | |rowspan="2" |A | ||
+ | |- | ||
+ | |<math>Kcat</math> | ||
+ | |Z | ||
+ | |<math> min^{-1} </math> | ||
|- | |- | ||
− | |rowspan=" | + | |rowspan="2" | [[Transformation of PGH2 to PGD2 |Transformation of PGH2 to PGD2]] |
+ | |rowspan="2" | PGDS | ||
+ | |rowspan="2" | 5.3.99.2 | ||
|<math>Km</math> | |<math>Km</math> | ||
− | | | + | |X |
|<math> nM </math> | |<math> nM </math> | ||
− | + | |rowspan="2" |Y | |
+ | |rowspan="2" |A | ||
+ | |- | ||
+ | |<math>Kcat</math> | ||
+ | |Z | ||
+ | |<math> min^{-1} </math> | ||
+ | |- | ||
+ | |rowspan="2" | [[Transformation of PGH2 to PGE2 |Transformation of PGH2 to PGE2]] | ||
+ | |rowspan="2" | PGES | ||
+ | |rowspan="2" | 5.3.99.3 | ||
+ | |<math>Km</math> | ||
+ | |X | ||
+ | |<math> nM </math> | ||
+ | |rowspan="2" |Y | ||
+ | |rowspan="2" |A | ||
|- | |- | ||
|<math>Kcat</math> | |<math>Kcat</math> | ||
− | | | + | |Z |
|<math> min^{-1} </math> | |<math> min^{-1} </math> | ||
+ | |} | ||
+ | |||
+ | == Overview of Feedback Parameters == | ||
+ | |||
+ | {|class="wikitable" | ||
+ | <table border='1' style="text-align:center"> | ||
+ | ! Feedback | ||
+ | ! Parameter | ||
+ | ! Value | ||
+ | ! Unit | ||
+ | ! Species | ||
+ | |- | ||
+ | | | ||
+ | |<math>Ki</math> | ||
+ | |X | ||
+ | |<math> μM </math> | ||
+ | |Y | ||
+ | |} | ||
+ | |||
+ | == Overview of Product Inhibition Parameters == | ||
+ | |||
+ | {|class="wikitable" | ||
+ | <table border='1' style="text-align:center"> | ||
+ | ! Species | ||
+ | ! Parameter | ||
+ | ! Value | ||
+ | ! Unit | ||
+ | ! Species | ||
+ | |- | ||
+ | | | ||
+ | |<math>Ki</math> | ||
+ | |X | ||
+ | |<math> μM </math> | ||
+ | |Y | ||
+ | |} | ||
+ | == Overview of Decay Parameters == | ||
+ | {|class="wikitable" | ||
+ | <table border='1' style="text-align:center"> | ||
+ | ! Species | ||
+ | ! Parameter | ||
+ | ! Value | ||
+ | ! Unit | ||
+ | ! Species | ||
+ | |- | ||
+ | | | ||
+ | |<math>Kd</math> | ||
+ | |X | ||
+ | |<math> μM </math> | ||
+ | |Y | ||
|} | |} | ||
+ | |||
+ | == Models == | ||
+ | |||
+ | Insert models for keratinocytes and fibroblasts here | ||
+ | |||
+ | == References == | ||
+ | <references/> |
Latest revision as of 16:50, 4 February 2016
Contents
Overview of Reaction Parameters
Reaction | Enzyme | E.C. | Parameter | Value | Unit | Species |
---|---|---|---|---|---|---|
Transformation of FA to AA | PLA2 | 3.1.1.4 | X | Failed to parse (Cannot store math image on filesystem.): μM | Y | |
Transformation of AA to PGH2 | COX-2 | 1.14.99.1 | X | Failed to parse (Cannot store math image on filesystem.): μM | Y | |
Transformation of PGH2 to PGF2α | PGFS | 1.1.1.188 | X | Y | ||
Transformation of PGH2 to TXA2 | TXAS | 5.3.99.5 | X | Y | ||
Transformation of PGH2 to PGI2 | PGIS | 5.3.99.4 | X | Y | ||
Transformation of PGH2 to PGD2 | PGDS | 5.3.99.2 | X | Y | ||
Transformation of PGH2 to PGE2 | PGES | 5.3.99.3 | X | Y | ||
Transformation of TXA2 to TXB2 | X | Y | ||||
Transformation of PGI2 to 6-K-PGF1α | X | Y | ||||
Transformation of PGD2 to PGJ2 | X | Y | ||||
Transformation of PGJ2 to 15-D-PGJ2 | X | Y |
Overview of Enzyme Parameters
A collection of literature parameters related to the model can be found here.
Reaction | Enzyme | E.C. | Parameter | Value | Unit | Species | Reference |
---|---|---|---|---|---|---|---|
Transformation of FA to AA | PLA2 | 3.1.1.4 | Failed to parse (Cannot store math image on filesystem.): Km | X | Failed to parse (Cannot store math image on filesystem.): μM | Y | A |
Failed to parse (Cannot store math image on filesystem.): Kcat | Z | ||||||
Transformation of AA to PGH2 | COX-2 | 1.14.99.1 | Failed to parse (Cannot store math image on filesystem.): Km | X | Failed to parse (Cannot store math image on filesystem.): μM | Y | A |
Failed to parse (Cannot store math image on filesystem.): Kcat | Z | ||||||
Transformation of PGH2 to PGF2α | PGFS | 1.1.1.188 | Failed to parse (Cannot store math image on filesystem.): Km | X | Failed to parse (Cannot store math image on filesystem.): μM | Y | A |
Failed to parse (Cannot store math image on filesystem.): Kcat | Z | ||||||
Transformation of PGH2 to TXA2 | TXAS | 5.3.99.5 | Failed to parse (Cannot store math image on filesystem.): Km | X | Failed to parse (Cannot store math image on filesystem.): μM | Y | A |
Failed to parse (Cannot store math image on filesystem.): Kcat | Z | ||||||
Transformation of PGH2 to PGI2 | PGIS | 5.3.99.4 | Failed to parse (Cannot store math image on filesystem.): Km | X | Failed to parse (Cannot store math image on filesystem.): μM | Y | A |
Failed to parse (Cannot store math image on filesystem.): Kcat | Z | ||||||
Transformation of PGH2 to PGD2 | PGDS | 5.3.99.2 | Failed to parse (Cannot store math image on filesystem.): Km | X | Y | A | |
Failed to parse (Cannot store math image on filesystem.): Kcat | Z | ||||||
Transformation of PGH2 to PGE2 | PGES | 5.3.99.3 | Failed to parse (Cannot store math image on filesystem.): Km | X | Y | A | |
Failed to parse (Cannot store math image on filesystem.): Kcat | Z |
Overview of Feedback Parameters
Feedback | Parameter | Value | Unit | Species |
---|---|---|---|---|
Failed to parse (Cannot store math image on filesystem.): Ki | X | Failed to parse (Cannot store math image on filesystem.): μM | Y |
Overview of Product Inhibition Parameters
Species | Parameter | Value | Unit | Species |
---|---|---|---|---|
Failed to parse (Cannot store math image on filesystem.): Ki | X | Failed to parse (Cannot store math image on filesystem.): μM | Y |
Overview of Decay Parameters
Species | Parameter | Value | Unit | Species |
---|---|---|---|---|
Failed to parse (Cannot store math image on filesystem.): Kd | X | Failed to parse (Cannot store math image on filesystem.): μM | Y |
Models
Insert models for keratinocytes and fibroblasts here