Transformation of PGH2 to PGF2α
Contents
Reaction
Chemical equation
Rate equation
Parameters
| Value | Units | Species | Notes | Reference |
|---|---|---|---|---|
| 1.90E-03 ± 1.5E-03 | 
|
Human | Placental Aldose Reductase (AKR1B1) | [1] |
| 1.80E-02 |
|
Human | Lung PGF2a Synthase (AKR1C3) | [1] |
| Value | Units | Species | Notes | Reference |
|---|---|---|---|---|
| 14.9 | per minute | Mouse/Swine | Prostamide/PGF Synthase Purified
from Swine Brain and of Murine Enzyme Expressed in E. coli |
[2] |
| Value | Units | Species | Notes | Reference |
|---|---|---|---|---|
| 105 | 
|
Human | Expression Vector: Platelet
Enzyme: PGFS pH: 7.5 Temperature: 37 °C |
[3] |
| 19.9 |
|
Human | Expression Vector: Lung
Enzyme: PGFS pH: 7.5 Temperature: 37 °C |
[4] |
| 40.3 |
|
Human | Expression Vector: Esophagus
Enzyme: PGFS pH: 7.5 Temperature: 37 °C |
[4] |
| 110 |
|
Human | Expression Vector: Oral Cavity
Enzyme: PGFS pH: 7.5 Temperature: 37 °C |
[4] |
References
- ↑ 1.0 1.1 Z. Kabututu, M. Manin, Prostaglandin F2alpha synthase activities of aldo-keto reductase 1B1, 1B3 and 1B7. J Biochem 2009,145(2):161-8)
- ↑ Moriuchi H., Molecular characterization of a novel type of prostamide/prostaglandin F synthase, belonging to the thioredoxin-like superfamily. J Biol Chem. 2008 Jan 11;283(2):792-801.)
- ↑ M. Kim A draft map of the human proteome Nature, 2014 509, 575–581
- ↑ 4.0 4.1 4.2 M. Wilhelm Mass-spectrometry-based draft of the human proteome Nature, 2014 509, 582–587
