Transformation of PGH2 to PGF2α

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Reaction

R3 PGH2 -PGF2A.jpg

Chemical equation

 FA \rightleftharpoons AA

Rate equation

Parameters

Michaelis-Menten Constants
Value Units Species Notes Reference
1.90E-03 ± 1.5E-03  mM Human Placental Aldose Reductase (AKR1B1) [1]
1.80E-02  mM  Human Lung PGF2a Synthase (AKR1C3) [1]
Enzyme Turnover Numbers
Value Units Species Notes Reference
0.2467 per second House Mouse pH 7.0, 24°C [1]

References

  1. 1.0 1.1 1.2 Z. Kabututu, M. Manin, Prostaglandin F2alpha synthase activities of aldo-keto reductase 1B1, 1B3 and 1B7. J Biochem 2009,145(2):161-8) Cite error: Invalid <ref> tag; name "Kabututu2009" defined multiple times with different content


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