Difference between revisions of "Transformation of PGH2 to PGF2α"

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(Parameters)
(Parameters)
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! Reference
 
! Reference
 
|-
 
|-
| 5.4
+
| 14.9
 
| per minute
 
| per minute
| House Mouse
+
| Mouse/Swine
| pH 7.0, 24°C
+
| Prostamide/PGF Synthase Purified
 +
from Swine Brain and of Murine Enzyme Expressed in E. coli
 
| <ref name="Moriuchi2008"> [http://www.ncbi.nlm.nih.gov/pubmed/18006499 Moriuchi H., Molecular characterization of a novel type of prostamide/prostaglandin F synthase, belonging to the thioredoxin-like superfamily.'' J Biol Chem. 2008 Jan 11;283(2):792-801.)]</ref>  
 
| <ref name="Moriuchi2008"> [http://www.ncbi.nlm.nih.gov/pubmed/18006499 Moriuchi H., Molecular characterization of a novel type of prostamide/prostaglandin F synthase, belonging to the thioredoxin-like superfamily.'' J Biol Chem. 2008 Jan 11;283(2):792-801.)]</ref>  
 
|}
 
|}

Revision as of 16:12, 10 April 2016

Return to overview

Reaction

R3 PGH2 -PGF2A.jpg

Chemical equation

 FA \rightleftharpoons AA

Rate equation

Parameters

Michaelis-Menten Constants
Value Units Species Notes Reference
1.90E-03 ± 1.5E-03  mM Human Placental Aldose Reductase (AKR1B1) [1]
1.80E-02  mM  Human Lung PGF2a Synthase (AKR1C3) [1]
Enzyme Turnover Numbers
Value Units Species Notes Reference
14.9 per minute Mouse/Swine Prostamide/PGF Synthase Purified

from Swine Brain and of Murine Enzyme Expressed in E. coli

[2]

References


Related Reactions