Transformation of PGH2 to PGD2

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Reaction

R21 PGH2 - PGD2.jpg

Chemical equation

FA \rightleftharpoons AA

Rate equation

Parameters

Michaelis-Menten Constants
Value Units Species Notes Reference
4.00E-03 mM Human Cerebrospinal Fluid [1]
4.00E-03 mM Human Human Wild Type Enzyme [2]
Enzyme Turnover Numbers
Value Units Species Notes Reference
158.4 per minute Human Wild type (Paper includes 13 mutants of the enzyme) [2]
Enzyme Concentrations
Value Units Species Notes Reference
0.000256 mM Human 20 ug/3ml of a 26 kDa protein. Cerebral Fluid. [1]
0.769 mM Human 20mg/ml of 26 kDa protein [2]

References

  1. ↑ 1.0 1.1 Watanabe K. , "Structure-function analysis of human l-prostaglandin D synthase bound with fatty acid molecules. Biochem Biophys Res Commun. 1994 Sep 15;203(2):1110-6.
  2. ↑ 2.0 2.1 2.2 Zhou Y. , "Identification of beta-trace as prostaglandin D synthase. FASEB J. 2010 Dec;24(12):4668-77. doi: 10.1096/fj.10-164863. Epub 2010 Jul 28. Cite error: Invalid <ref> tag; name "Zhou2010" defined multiple times with different content Cite error: Invalid <ref> tag; name "Zhou2010" defined multiple times with different content

Related Reactions

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