Transformation of LTA4 to LTC4
Contents
Reaction
Chemical equation
Rate equation
Parameters
Value | Units | Species | Notes | Reference |
---|---|---|---|---|
0.3 �± 0.06 | mM | Human | Wild Type hLTC4S, 20 °C, pH 7.8, incubated for 15 seconds. | [1] |
3.00E-02 ± 1.00E-02 | mM | Human | Wild type, pH 7.8 | [2] |
Value | Units | Species | Notes | Reference |
---|---|---|---|---|
702 | per minute | Human | Wild Type hLTC4S, 20 °C, pH 7.8, incubated for 15 seconds. | [1] |
1560 ± 240 | per minute | Human | Wild Type, pH 7.8 | [2] |
References
- ↑ 1.0 1.1 [http://www.ncbi.nlm.nih.gov/pubmed/19010934 Rinaldo A. " Arginine 104 Is a Key Catalytic Residue in Leukotriene C4 Synthase J Biochem 2010, 285, 40771-40776]
- ↑ 2.0 2.1 [http://www.ncbi.nlm.nih.gov/pubmed/19010934 Niegowski D. " Crystal structures of Leukotriene C4 synthase in complex with product analogs, implications for the enzyme mechanism J. Biol. Chem. 289, 5199-5207 (2014)]