Difference between revisions of "Transformation of LTA4 to LTC4"
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! Reference | ! Reference | ||
|- | |- | ||
| − | + | |0.3 �± 0.06 | |
| + | |mM | ||
| + | |Human | ||
| + | |Wild Type hLTC4S, 20 °C, pH 7.8, incubated for 15 seconds. | ||
| + | |<ref name="Rinaldo2010"> [http://www.ncbi.nlm.nih.gov/pubmed/19010934 Rinaldo A. " Arginine 104 Is a Key Catalytic Residue in Leukotriene C4 | ||
| + | Synthase'' J Biochem 2010, 285, 40771-40776]</ref> | ||
| + | |- | ||
| + | |3.00E-02 ± 1.00E-02 | ||
| + | |mM | ||
| + | |Human | ||
| + | |Wild type, pH 7.8 | ||
| + | |<ref name="Niegowski2013"> [http://www.ncbi.nlm.nih.gov/pubmed/19010934 Niegowski D. " Crystal structures of Leukotriene C4 synthase in complex with product analogs, implications for the | ||
| + | enzyme mechanism'' J. Biol. Chem. 289, 5199-5207 (2014)]</ref> | ||
| + | |- | ||
|} | |} | ||
| Line 34: | Line 47: | ||
! Reference | ! Reference | ||
|- | |- | ||
| − | + | |702 | |
| − | + | |per minute | |
| + | |Human | ||
| + | |Wild Type hLTC4S, 20 °C, pH 7.8, incubated for 15 seconds. | ||
| + | |<ref name="Rinaldo2010"> [http://www.ncbi.nlm.nih.gov/pubmed/19010934 Rinaldo A. " Arginine 104 Is a Key Catalytic Residue in Leukotriene C4 | ||
| + | Synthase'' J Biochem 2010, 285, 40771-40776]</ref> | ||
| + | |- | ||
| + | |1560 ± 240 | ||
| + | |per minute | ||
| + | |Human | ||
| + | |Wild Type, pH 7.8 | ||
| + | |<ref name="Niegowski2013"> [http://www.ncbi.nlm.nih.gov/pubmed/19010934 Niegowski D. " Crystal structures of Leukotriene C4 synthase in complex with product analogs, implications for the | ||
| + | enzyme mechanism'' J. Biol. Chem. 289, 5199-5207 (2014)]</ref> | ||
| + | |- | ||
|} | |} | ||
== Related Reactions == | == Related Reactions == | ||
Revision as of 15:02, 11 April 2016
Reaction
Chemical equation
Rate equation
Parameters
| Value | Units | Species | Notes | Reference |
|---|---|---|---|---|
| 0.3 �± 0.06 | mM | Human | Wild Type hLTC4S, 20 °C, pH 7.8, incubated for 15 seconds. | [1] |
| 3.00E-02 ± 1.00E-02 | mM | Human | Wild type, pH 7.8 | [2] |
| Value | Units | Species | Notes | Reference |
|---|---|---|---|---|
| 702 | per minute | Human | Wild Type hLTC4S, 20 °C, pH 7.8, incubated for 15 seconds. | [1] |
| 1560 ± 240 | per minute | Human | Wild Type, pH 7.8 | [2] |
Related Reactions
- ↑ 1.0 1.1 [http://www.ncbi.nlm.nih.gov/pubmed/19010934 Rinaldo A. " Arginine 104 Is a Key Catalytic Residue in Leukotriene C4 Synthase J Biochem 2010, 285, 40771-40776]
- ↑ 2.0 2.1 [http://www.ncbi.nlm.nih.gov/pubmed/19010934 Niegowski D. " Crystal structures of Leukotriene C4 synthase in complex with product analogs, implications for the enzyme mechanism J. Biol. Chem. 289, 5199-5207 (2014)]
