Difference between revisions of "Transformation of 5-HETE to 5-OXO-ETE"
(Created page with " Return to overview == Reaction == center|500px ==Chemical equation== <center><ma...") |
|||
| Line 1: | Line 1: | ||
[[Welcome to the In-Silico Model of Cutaneous Lipids Wiki | Return to overview]] | [[Welcome to the In-Silico Model of Cutaneous Lipids Wiki | Return to overview]] | ||
| + | |||
| + | The metabolism of 5-HETE to 5-Oxo-ETE is catalysed by the enzyme 5-Hydroxyeicosanoid dehydrogenase (5-HEDH). This enzyme acts reversibly and has been reported to be found in skin (need to check). The product binds with the OXE receptor (Hosoi2002) and is 30-100 more bioactive than 5-HETE. 5-Oxo-ETE is a chemoattractant for neutrophils and eosinophils. | ||
| + | |||
== Reaction == | == Reaction == | ||
| Line 6: | Line 9: | ||
==Chemical equation== | ==Chemical equation== | ||
| − | <center><math> | + | <center><math> 5-HETE \rightleftharpoons 5-Oxo-ETE </math></center> |
== Rate equation == | == Rate equation == | ||
Revision as of 13:51, 30 September 2016
The metabolism of 5-HETE to 5-Oxo-ETE is catalysed by the enzyme 5-Hydroxyeicosanoid dehydrogenase (5-HEDH). This enzyme acts reversibly and has been reported to be found in skin (need to check). The product binds with the OXE receptor (Hosoi2002) and is 30-100 more bioactive than 5-HETE. 5-Oxo-ETE is a chemoattractant for neutrophils and eosinophils.
Reaction
Chemical equation
Rate equation
Parameters
| Name | Value | Units | Species | Reference |
|---|---|---|---|---|
| X | Y | Z | A | B |
