Difference between revisions of "Transformation of 12-HPETE to 12-HETE"
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==Chemical equation== | ==Chemical equation== | ||
| − | <center><math> | + | <center><math> 12-HPETE \rightleftharpoons 12-HETE </math></center> |
== Rate equation == | == Rate equation == | ||
Revision as of 14:28, 26 September 2017
12-HPETE is reduced by phospholipid hydroperoxide glutathione peroxidase (PHGPx) to the corresponding alcohol, 12-HETE (Suth01). 12-HETE is found in high concentrations in the skin and is renowned for acting as a chemoattractant during inflammation, with binding sites on both LCs and keratinocyte cells (Dowd, Kobza Black et al. 1985).
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