Difference between revisions of "Transformation of 12-HPETE to 12-HETE"

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(Parameters)
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== Rate equation ==
 
== Rate equation ==
  
 +
[[File:R20.PNG |center|500px]]
  
 
== Parameters ==
 
== Parameters ==

Revision as of 14:28, 26 September 2017

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12-HPETE is reduced by phospholipid hydroperoxide glutathione peroxidase (PHGPx) to the corresponding alcohol, 12-HETE (Suth01). 12-HETE is found in high concentrations in the skin and is renowned for acting as a chemoattractant during inflammation, with binding sites on both LCs and keratinocyte cells (Dowd, Kobza Black et al. 1985).

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R20 HPETE12 - HETE12.jpg

Chemical equation

 AA \rightleftharpoons PGH2

Rate equation

R20.PNG

Parameters

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