Difference between revisions of "Transformation of 12-HPETE to 12-HETE"
| Line 1: | Line 1: | ||
[[Welcome to the In-Silico Model of Cutaneous Lipids Wiki | Return to overview]] | [[Welcome to the In-Silico Model of Cutaneous Lipids Wiki | Return to overview]] | ||
| + | |||
| + | 12-HPETE is reduced by phospholipid hydroperoxide glutathione peroxidase (PHGPx) to the corresponding alcohol, 12-HETE (Suth01). 12-HETE is found in high concentrations in the skin and is renowned for acting as a chemoattractant during inflammation, with binding sites on both LCs and keratinocyte cells (Dowd, Kobza Black et al. 1985). | ||
| + | |||
== Reaction == | == Reaction == | ||
Revision as of 14:38, 31 August 2016
12-HPETE is reduced by phospholipid hydroperoxide glutathione peroxidase (PHGPx) to the corresponding alcohol, 12-HETE (Suth01). 12-HETE is found in high concentrations in the skin and is renowned for acting as a chemoattractant during inflammation, with binding sites on both LCs and keratinocyte cells (Dowd, Kobza Black et al. 1985).
Reaction
Chemical equation
Rate equation
Parameters
| Name | Value | Units | Species | Reference |
|---|---|---|---|---|
| X | Y | Z | A | B |
