Difference between revisions of "Formation of homo-dimer R2"
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Revision as of 02:50, 5 October 2015
Two ScbR (R) proteins bind together to form an ScbR homo-dimer (R2).
Contents
Chemical equation
Rate equation
![r= \frac{k^{-}_{6}}{K_{d6}}\cdot [R]^{2} - k^{-}_{6}\cdot [R_{2}]](/wiki/images/math/b/d/2/bd256ae2f0b0944a1e29766d6d3329ee.png)
Parameters
The parameters of this reaction are the dissociation constant for binding of one ScbR to another (
) and the dissociation rate for binding of one ScbR to another (
).
| Name | Value | Units | Origin | Remarks |
|---|---|---|---|---|
|
|
 [1]
|
|
Studies with Streptomyces DnaA Protein | |
|
|
 [2] [3]
|
|
Strong protein-protein interactions rate constants |
Parameters with uncertainty
References
- ↑ Majka J, Zakrzewska-Czerwiñska J, Messer W. Sequence recognition, cooperative interaction, and dimerization of the initiator protein DnaA of Streptomyces. J Biol Chem. 2001;276(9):6243-52.
- ↑ Wesley E. Stites. Protein−Protein Interactions: Interface Structure, Binding Thermodynamics, and Mutational Analysis. Chemical Reviews 1997 97 (5), 1233-1250
- ↑ Janin, Joel. The kinetics of protein-protein recognition. Proteins-Structure Function and Bioinformatics (1997): 153-161.
