Difference between revisions of "Degradation of Ce"

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== Parameters ==
 
== Parameters ==
  
The parameter of this reaction is the degradation rate of C<sub>e</sub> (<math>d_{C}</math>), which is assumed to be the same as with the cellular SCB1 (C).
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The parameter of this reaction is the degradation rate of C<sub>e</sub> (<math>d_{C}</math>), which is assumed to be the same as the degradation of the cellular SCB1 (C). Detailed information on this parameter can be found [[Degradation of C|here]].
 
 
{|class="wikitable"
 
! Name
 
! Value
 
! Units
 
! Origin
 
! Remarks
 
|-
 
|<math>d_{C}</math>
 
|<math>0-0.001</math> <ref name="Trötschel2013"> S. Basu, Y. Gerchman, C. H. Collins, F. H. Arnold & R. Weiss. ''A synthetic multicellular system for programmed pattern formation''. Nature 434, 1130-1134, 2005</ref>
 
| <math>min^{-1}</math>
 
| Degradation rate of acyl-homoserine lactone (AHL)
 
| The assumption that the degradation of SCB1 is slower than
 
AHL is made, as described in Takano(2006)<ref name="Takano2006"> E. Takano. ''γ-butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation.'' Current Opinion in Microbiology, 9(3):287–294, 2006.</ref>
 
|}
 
  
 
==Parameters with uncertainty==
 
==Parameters with uncertainty==

Revision as of 19:46, 17 October 2015

The extracellular SCB1 protein (Ce) degrades.

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Chemical equation

C_{e}\rightarrow \varnothing

Rate equation

 r= d_{C}\cdot[C_{e}]

Parameters

The parameter of this reaction is the degradation rate of Ce (d_{C}), which is assumed to be the same as the degradation of the cellular SCB1 (C). Detailed information on this parameter can be found here.

Parameters with uncertainty

The most plausible parameter value for the d_{C} is decided to be  0.0002 min^{-1} and the confidence interval  2 . This means that the mode of the PDF is 0.0002 and the range where 95% of the values are found is between 0.0001 and 0.0004 min^{-1}.

The probability distribution for the parameter, adjusted accordingly in order to reflect the above values, is the following:

500px

The location and scale parameters of the distribution are:

Parameter μ σ
d_{C} -8.4046 0.3356

References