Degradation of C2-R2

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The SCB-ScbR protein complex (C2R2) degrades.

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Chemical equation

C_{2}R_{2}\rightarrow \varnothing

Rate equation

 r= d_{CR}\cdot[C_{2}R_{2}]

Parameters

The parameter of this reaction is the degradation rate of C2R2 (d_{CR}).

Name Value Units Origin Remarks
d_{CR} 0.000833-0.001667 [1] min^{-1} Degradation rates of proteins in S. coelicolor

based on radioactive decay

Parameters with uncertainty

The most plausible parameter value for the d_{CR} is decided to be  0.00118 min^{-1} and the confidence interval  1.41 . This means that the mode of the PDF is 0.00118 and the range where 95% of the values are found is between 0.8369\cdot 10^{-3} and 1.67 \cdot 10^{-3} min^{-1}.

The probability distribution for the parameter, adjusted accordingly in order to reflect the above values, is the following:

DCR.png

The location and scale parameters of the distribution are:

Parameter μ σ
d_{CR} -6.7120 0.174

References

  1. Trötschel C, Albaum SP, Poetsch A. Proteome turnover in bacteria: current status for Corynebacterium glutamicum and related bacteria. Microbial biotechnology. 2013;6(6):708-719.