Difference between revisions of "ATP-Binding Cassette Transporters"

Revision as of 15:04, 19 May 2016

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Michaelis-Menten Constants
Value	Units	Species	Notes	Reference
0.0109 ± 0.00391	mM	Human	Substrate: LTC4 pH 7.0, 37°C, recombinant MRP2, using 4mM MgATP and 5g of isolated membranes.	^[1]

Protein Concentrations
Value	Units	Species	Notes	Reference

Vmax ***
Value	Units	Species	Notes	Reference
190.9 ± 19.6	nmol Pi/min/mg protein	Human	Substrate: LTC4 pH 7.0, 37°C, recombinant MRP2, using 4mM MgATP and 5g of isolated membranes.	^[1]

@@ Line 24: / Line 24: @@
 |Human
 |Substrate: LTC4
-pH 7.0, 37°C, recombinant MRP2
+pH 7.0, 37°C, recombinant MRP2, using 4mM MgATP and 5g of isolated membranes.
 |<ref name="Yas2007"> [http://ac.els-cdn.com/S0928098708003618/1-s2.0-S0928098708003618-main.pdf?_tid=a147bd90-1dc8-11e6-9405-00000aab0f26&acdnat=1463666001_5a08a971497da36ce8a604f84caadfc2 Yasunaga M. "Molecular cloning and functional characterization of cynomolgus monkey multidrug resistance-associated protein 2 (MRP2)''  Eur. J. Pharm. Sci. 35, 326-334 (2008)]</ref>
 |-
@@ Line 54: / Line 54: @@
 |Human
 |Substrate: LTC4
-pH 7.0, 37°C, recombinant MRP2
+pH 7.0, 37°C, recombinant MRP2, using 4mM MgATP and 5g of isolated membranes.
 |<ref name="Yas2007"> [http://ac.els-cdn.com/S0928098708003618/1-s2.0-S0928098708003618-main.pdf?_tid=a147bd90-1dc8-11e6-9405-00000aab0f26&acdnat=1463666001_5a08a971497da36ce8a604f84caadfc2 Yasunaga M. "Molecular cloning and functional characterization of cynomolgus monkey multidrug resistance-associated protein 2 (MRP2)''  Eur. J. Pharm. Sci. 35, 326-334 (2008)]</ref>
 |-