Difference between revisions of "Transformation of 12-HPETE to 12-HETE"
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== Parameters == | == Parameters == | ||
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* [[Transformation of 5-HPETE to 5-HETE |See PHGPx parameters here. ]] | * [[Transformation of 5-HPETE to 5-HETE |See PHGPx parameters here. ]] | ||
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== Related Reactions == | == Related Reactions == | ||
Revision as of 13:38, 31 August 2016
12-HPETE is reduced by phospholipid hydroperoxide glutathione peroxidase (PHGPx) to the corresponding alcohol, 12-HETE (Suth01). 12-HETE is found in high concentrations in the skin and is renowned for acting as a chemoattractant during inflammation, with binding sites on both LCs and keratinocyte cells (Dowd, Kobza Black et al. 1985).
Reaction
Chemical equation
