View source for Transformation of 12-HPETE to 12-HETE

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12-HPETE is reduced by phospholipid hydroperoxide glutathione peroxidase (PHGPx) to the corresponding alcohol, 12-HETE (Suth01). 12-HETE is found in high concentrations in the skin and is renowned for acting as a chemoattractant during inflammation, with binding sites on both LCs and keratinocyte cells (Dowd, Kobza Black et al. 1985).

== Reaction ==

[[File:R20_HPETE12_-_HETE12.jpg  |center|500px]]

==Chemical equation==

<center><math> 12-HPETE \rightleftharpoons 12-HETE </math></center>

== Rate equation ==

[[File:R20.PNG |center|500px]]

== Parameters ==
* [[Transformation of 5-HPETE to 5-HETE |See PHGPx parameters here. ]]

== Related Reactions ==