Transformation of AA to 8,9-EET to 8,9-DHET

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Reaction

Chemical equation

AA \rightleftharpoons 20-HETE

Rate equation

CYP Parameters

Michaelis-Menten Constants
Value Units Species Notes Reference
mM Human Expression Vector:

Enzyme: pH: Temperature:

[1]
Enzyme Turnover Numbers
Value Units Species Notes Reference
per minute Expression Vector:

Enzyme: pH: Temperature:

[2]


CYP Abundance
Value Units Species Notes Reference
ppm Human Expression Vector:

Enzyme: pH: Temperature:

[3]
Gibbs Free Energy Change
Value Units Species Notes Reference
kcal/mol Expression Vector:

Enzyme: pH: Temperature:

[4]

References

  1. ↑ Soberman R. J. “Characterization and separation of the arachidonic acid 5-lipoxygenase and linoleic acid omega-6 lipoxygenase (arachidonic acid 15-lipoxygenase) of human polymorphonuclear leukocytes.” J Biol Chem. 1985 Apr 10;260(7):4508-15.
  2. ↑ Mulliez E., “5-Lipoxygenase from potato tubers. Improved purification and physicochemical characteristics” Biochimica et Biophysica Acta, 1987;916(1):13-23.
  3. ↑ M. Kim A draft map of the human proteome Nature, 2014 509, 575–581
  4. ↑ Caspi et al 2014, "The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases," Nucleic Acids Research 42:D459-D471


Related Reactions

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