Decay of PGJ2 to exPGJ2

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Rate equation

R51.PNG

Decay Parameters

Literature values
Reaction # Species Half Life (min) Rate constant(min -1) Notes Weights Reference
51 exPGJ2 720 0.001 Assumed the same as ex15-DEOXY-PGJ2 -
Dehydration of PGD2 to ultimatley 15d-PGJ2 occurs with a half life of about 12 hours in the presense of albumin (protien found in blood).
8 [1]
Description of the PGJ2 decay constant distribution
Mode (min-1) Confidence Interval Location parameter (µ) Scale parameter (σ)
9.95E-04 1.10E+00 -6.90E+00 9.49E-02
The estimated probability distribution for PGJ2 decay constant. The value and weight of the literature values used to define the distribution are indicated by an orange dashed line. The x axis is plotted on a log-scale.
The estimated probability distribution for exPGJ2 decay constant. The value and weight of the literature values used to define the distribution are indicated by an orange dashed line. The x axis is plotted on a log-scale.

References