Decay of 12-HETE to ex12-HETE

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Rate equation

Decay Parameters

Literature values

Reaction #	Species	Half Life (min)	Rate constant(min -1)	Notes	Weight	Reference
62	ex12-HETE	180	0.004	"During the first 2 min., the half-life of 12-HETE was 0.9 s, which implies a fast clearance of the compound from the circulation. However, during the subsequent half-hour the estimated half-life was 3 min. and increased dramatically at the interval of time from 30 to 60 min. (t1/2 around 3 h)."	8

Description of the 12-HETE decay constant distribution

Mode (min-1)	Confidence Interval	Location parameter (µ)	Scale parameter (σ)
3.83E-03	1.10E+00	-5.56E+00	9.49E-02

The estimated probability distribution for 12-HETE decay constant. The value and weight of the literature values used to define the distribution are indicated by an orange dashed line. The x axis is plotted on a log-scale.

The estimated probability distribution for ex12-HETE decay constant. The value and weight of the literature values used to define the distribution are indicated by an orange dashed line. The x axis is plotted on a log-scale.