Translation of R

The scbR mRNA (r) is translated into ScbR protein (R).

Chemical equation

$r \rightarrow r + R$

Rate equation

$r= P_{R}\cdot [r]$

Parameters

The parameter of this reaction is the translation rate of ScbR ($P_{R}$).

Name	Value	Units	Origin	Remarks
$P_{R}$	Failed to parse (Cannot store math image on filesystem.): 0.88	$min^{-1}$	Streptomyces coelicolor A3(2)	Translation values were calculated according to the rates proposed in the paper by R.A. Cox using the basepairs for each gene.For scbR the initiation rate is 5 $min^{-1}$ and the elongation rate is (648/3-1 aa/gene)/(14 aa/Failed to parse (Cannot store math image on filesystem.): s )= 15.36, thus resulting in a final value of 0.88 $min^{-1}$. Since the elongation is slower than the initiation, we conclude that it is the limiting step.

Parameters with uncertainty

The most plausible parameter value for the $P_{R}$ is decided to be Failed to parse (Cannot store math image on filesystem.): 0.5 min^{-1} and the confidence interval $10$. This means that the mode of the PDF is 0.5 and the range where 95% of the values are found is between 0.05 and 5 $min^{-1}$.

The probability distribution for the parameter, adjusted accordingly in order to reflect the above values, is the following:

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The location and scale parameters of the distribution are:

Parameter	μ	σ
$P_{R}$	Failed to parse (Cannot store math image on filesystem.): 0.1220	$0.9028$