Translation of A

The scbA mRNA (a) is translated into ScbA protein (A).

Chemical equation

$a \rightarrow a + A$

Rate equation

$r= P_{A}\cdot [a]$

Parameters

The parameter of this reaction is the translation rate of ScbA ($P_{A}$).

Name	Value	Units	Origin	Remarks
$P_{A}$	Failed to parse (Cannot store math image on filesystem.): 0.60	Failed to parse (Cannot store math image on filesystem.): min^{1}	Streptomyces coelicolor A3(2)	Translation values were calculated according to the rates proposed in the paper by R.A. Cox using the basepairs for each gene. For scbA the initiation rate is 5 $min^{-1}$ and the elongation rate is (945/3-1 aa/gene)/(14 aa/Failed to parse (Cannot store math image on filesystem.): s^{-1} )= , thus resulting in a final value of 0.60 $min^{-1}$. Since the elongation is slower than the initiation, we conclude that it is the limiting step.

Parameters with uncertainty

The most plausible parameter value for the $P_{R}$ is decided to be Failed to parse (Cannot store math image on filesystem.): 0.5 min^{-1} and the confidence interval $10$. This means that the mode of the PDF is 0.5 and the range where 95% of the values are found is between 0.05 and 5 $min^{-1}$.

The probability distribution for the parameter, adjusted accordingly in order to reflect the above values, is the following:

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The location and scale parameters of the distribution are:

Parameter	μ	σ
$P_{A}$	Failed to parse (Cannot store math image on filesystem.): 0.1220	$0.9028$