Transformation of PGH2 to TXA2
Contents
Reaction
Chemical equation
Rate equation
Parameters
Value | Units | Species | Notes | Reference |
---|---|---|---|---|
4.00E-03 | Human | Expression Vector: Human Monocyte
Enzyme: Platelet Free Human Monocyte pH: 7.4 Temperature: 37 |
[1] | |
1.00E-02 | Human | Expression Vector: Human mirosome
Enzyme: Human Thromboxane Synthase pH:7.4 Temperature: |
[2] | |
2.20E-02 | Human | Expression Vector:Human platelet
Enzyme: Human thromboxane synthase pH: 7.4 Temperature: 37 |
[3] |
Value | Units | Species | Notes | Reference |
---|---|---|---|---|
2687 | per minute | Human | Expression Vector: Human Platelets
Enzyme: TXAS pH: 7.4 Temperature:30 |
[4] |
1628 | per minute | Human | Expression Vector:Platelet Microsomes
Enzyme: TXAS pH:7.4 Temperature:37 |
[5] |
Value | Units | Species | Notes | Reference |
---|---|---|---|---|
949 | Human | Expression Vector: Platelet
Enzyme: TXAS pH: 7.5 Temperature: 37 °C |
[6] | |
56.2 | Human | Expression Vector: Lung
Enzyme: TXAS pH: 7.5 Temperature: 37 °C |
[6] | |
4.58 | Human | Expression Vector: Urinary Bladder
Enzyme: TXAS pH: 7.5 Temperature: 37 °C |
[6] | |
101 | Human | Expression Vector: Oral Cavity
Enzyme: TXAS pH: 7.5 Temperature: 37 °C |
[7] |
References
- ↑ M. Orlandi, G. Bartolini, Thromboxane A2 synthase activity in platelet free human monocytes. Biochim Biophys Acta. 1994 Dec 8;1215(3):285-90.
- ↑ R. Nusing, S. Schneider-Voss and V. Ullrich, Immunoaffinity purification of human thromboxane synthase. Arch Biochem Biophys. 1990 Aug 1;280(2):325-30.
- ↑ Hecker M. On the mechanism of prostacyclin and thromboxane A2 biosynthesis.J Biol Chem. 1989 Jan 5;264(1):141-50.
- ↑ [www.ncbi.nlm.nih.gov/pubmed/3579292 Hecker M. “Products, kinetics, and substrate specificity of homogeneous thromboxane synthase from human platelets: Development of a novel enzyme assay ” Arch. Biochem. Biophys. 1987, 254, 124-135]
- ↑ [www.ncbi.nlm.nih.gov/pubmed/2999104 Haurand M. “Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P-450 enzyme” J Biol Chem. 1985, 260 (5), 15059-15067]
- ↑ 6.0 6.1 6.2 M. Kim A draft map of the human proteome Nature, 2014 509, 575–581
- ↑ M. Wilhelm Mass-spectrometry-based draft of the human proteome Nature, 2014 509, 582–587