Difference between revisions of "Transformation of PGH2 to TXA2"
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|<ref name="Yang2008”>[http://www.ncbi.nlm.nih.gov/pubmed/18985027 Yang K. “Finding multiple target optimal intervention in disease-related molecular network.” Mol Syst Biol 2008, (4):228]</ref> | |<ref name="Yang2008”>[http://www.ncbi.nlm.nih.gov/pubmed/18985027 Yang K. “Finding multiple target optimal intervention in disease-related molecular network.” Mol Syst Biol 2008, (4):228]</ref> | ||
| + | |- | ||
| + | |2687 | ||
| + | |per minute | ||
| + | |Human | ||
| + | |Platelets | ||
| + | |<ref name="Hecker1987”>[www.ncbi.nlm.nih.gov/pubmed/3579292 Hecker M. “Products, kinetics, and substrate specificity of homogeneous thromboxane synthase from human platelets: Development of a novel enzyme assay ” Arch. Biochem. Biophys. 1987, 254, 124-135]</ref> | ||
| + | |- | ||
| + | |1628 | ||
| + | |per minute | ||
| + | |Human | ||
| + | |Platelet Microsomes | ||
| + | |<ref name="Haurand1985”>[www.ncbi.nlm.nih.gov/pubmed/2999104 Haurand M. “Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P-450 enzyme” J Biol Chem. 1985, 260 (5), 15059-15067]</ref> | ||
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Revision as of 16:30, 10 April 2016
Contents
Reaction
Chemical equation
Rate equation
Parameters
| Value | Units | Species | Notes | Reference |
|---|---|---|---|---|
| 4.00E-03 | 
|
Human | PMN | [1] |
| 4.00E-03 |
|
Human | Platelet Free Human Monocyte | [2] |
| 1.00E-02 |
|
Human | Human Thromboxane Synthase | [3] |
| 2.20E-02 |
|
Human | Wild-Type TXAS | [4] |
| Value | Units | Species | Notes | Reference |
|---|---|---|---|---|
| 1599 | Failed to parse (Cannot store math image on filesystem.): min{-1} | Human | PMN | [1] |
| 2687 | per minute | Human | Platelets | [5] |
| 1628 | per minute | Human | Platelet Microsomes | [6] |
References
- ↑ 1.0 1.1 Yang K. “Finding multiple target optimal intervention in disease-related molecular network.” Mol Syst Biol 2008, (4):228
- ↑ M. Orlandi, G. Bartolini, Thromboxane A2 synthase activity in platelet free human monocytes. Biochim Biophys Acta. 1994 Dec 8;1215(3):285-90.
- ↑ R. Nusing, S. Schneider-Voss and V. Ullrich, Immunoaffinity purification of human thromboxane synthase. Arch Biochem Biophys. 1990 Aug 1;280(2):325-30.
- ↑ Hecker M. On the mechanism of prostacyclin and thromboxane A2 biosynthesis.J Biol Chem. 1989 Jan 5;264(1):141-50.
- ↑ [www.ncbi.nlm.nih.gov/pubmed/3579292 Hecker M. “Products, kinetics, and substrate specificity of homogeneous thromboxane synthase from human platelets: Development of a novel enzyme assay ” Arch. Biochem. Biophys. 1987, 254, 124-135]
- ↑ [www.ncbi.nlm.nih.gov/pubmed/2999104 Haurand M. “Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P-450 enzyme” J Biol Chem. 1985, 260 (5), 15059-15067]
