Transformation of PGH2 to PGI2

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Reaction

R5 PGH2 - PGI2.jpg

Chemical equation

FA \rightleftharpoons AA

Rate equation

Parameters

Michaelis-Menten Constants
Value Units Species Notes Reference
1.33E-02 ± 1.40E-03 mM Human Human PGIS [1]
9.00E-03 ± 5.00E-03 mM Bovine Bovine Endothelial Cells [2]
Enzyme Turnover Numbers
Value Units Species Notes Reference
X Y Z A B

References

  1. ↑ H. C. Yeh, P. Y. Hsu, Characterization of heme environment and mechanism of peroxide bond cleavage in human prostacyclin synthase. Biochim Biophys Acta. 2005 Dec 30;1738(1-3):121-32.
  2. ↑ Hara S. , Isolation and molecular cloning of prostacyclin synthase from bovine endothelial cells. J Biol Chem. 1994 Aug 5;269(31):19897-903.

Related Reactions

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