Transformation of PGE2 to 15-Keto-PGE2

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Reaction

Catalysed by 15-PGDH

Chemical equation

$PGE2 \rightleftharpoons 15-Keto-PGE2$

15-PGDH Parameters

Michaelis-Menten Constants

Value	Units	Species	Notes	Reference
0.008	$mM$	Rat Skin	Method: pH:7.4 Temperature: 37'C Substrate: PGE2 + NAD+
0.0075	$mM$	Rat Skin	Method: pH:7.4 Temperature: 37'C Substrate: PGE2 + NADP+
0.024	$mM$	Rat Skin	Method: pH:7.4 Temperature: 37'C Substrate: PGF2a + NAD+
0.023	$mM$	Rat Skin	Method: pH:7.4 Temperature: 37'C Substrate: PGF2a + NADP+

Enzyme Turnover Numbers

Value	Units	Species	Notes	Reference
	$per minute$

cPLA2 Abundance

Value	Units	Species	Notes	Reference
	$ppm$

Gibbs Free Energy Change

Value	Units	Species	Notes	Reference