Difference between revisions of "Transformation of PGE2 to 15-Keto-PGE2"

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(Created page with " Return to overview == Reaction == Catalysed by 15-PGDH ==Chemical equation== <center><math> PGE2 \rightleft...")
 
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! Reference
 
! Reference
 
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|0.008
 
|<math> mM </math>
 
|<math> mM </math>
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| Rat Skin
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|Method:
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pH:7.4
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Temperature: 37'C
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Substrate: PGE2 + NAD+
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|<ref name="Fincham1982"> [https://www.ncbi.nlm.nih.gov/pubmed/6575778 N. Fincham, Novel prostaglandin dehydrogenase in rat skin.'' Biochem J. 1983 Apr 15;212(1):129-34.]</ref>
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|-
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|0.0075
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|<math> mM </math>
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| Rat Skin
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|Method:
 +
pH:7.4
 +
Temperature: 37'C
 +
Substrate: PGE2 + NADP+
 +
|<ref name="Fincham1982"> [https://www.ncbi.nlm.nih.gov/pubmed/6575778 N. Fincham, Novel prostaglandin dehydrogenase in rat skin.'' Biochem J. 1983 Apr 15;212(1):129-34.]</ref>
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|-
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|0.024
 +
|<math> mM </math>
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| Rat Skin
 +
|Method:
 +
pH:7.4
 +
Temperature: 37'C
 +
Substrate: PGF2a + NAD+
 +
|<ref name="Fincham1982"> [https://www.ncbi.nlm.nih.gov/pubmed/6575778 N. Fincham, Novel prostaglandin dehydrogenase in rat skin.'' Biochem J. 1983 Apr 15;212(1):129-34.]</ref>
 +
|-
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|0.023
 +
|<math> mM </math>
 +
| Rat Skin
 +
|Method:
 +
pH:7.4
 +
Temperature: 37'C
 +
Substrate: PGF2a + NADP+
 +
|<ref name="Fincham1982"> [https://www.ncbi.nlm.nih.gov/pubmed/6575778 N. Fincham, Novel prostaglandin dehydrogenase in rat skin.'' Biochem J. 1983 Apr 15;212(1):129-34.]</ref>
 
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Revision as of 15:50, 28 September 2016

Return to overview


Reaction

Catalysed by 15-PGDH

Chemical equation

PGE2 \rightleftharpoons 15-Keto-PGE2

Rate equation

15-PGDH Parameters

Michaelis-Menten Constants
Value Units Species Notes Reference
0.008 mM Rat Skin Method:

pH:7.4 Temperature: 37'C Substrate: PGE2 + NAD+

[1]
0.0075 mM Rat Skin Method:

pH:7.4 Temperature: 37'C Substrate: PGE2 + NADP+

[1]
0.024 mM Rat Skin Method:

pH:7.4 Temperature: 37'C Substrate: PGF2a + NAD+

[1]
0.023 mM Rat Skin Method:

pH:7.4 Temperature: 37'C Substrate: PGF2a + NADP+

[1]


Enzyme Turnover Numbers
Value Units Species Notes Reference
per minute
cPLA2 Abundance
Value Units Species Notes Reference
ppm
Gibbs Free Energy Change
Value Units Species Notes Reference

References

  1. ↑ 1.0 1.1 1.2 1.3 N. Fincham, Novel prostaglandin dehydrogenase in rat skin. Biochem J. 1983 Apr 15;212(1):129-34.
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