Difference between revisions of "Transformation of LTA4 to LTB4"
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! Reference | ! Reference | ||
|- | |- | ||
− | + | |5.80E-03 | |
+ | |mM | ||
+ | |Human | ||
+ | |Wild Type, pH 8.0, at room temperature. | ||
+ | |<ref name="Mueller1996"> [www.ncbi.nlm.nih.gov/pubmed/8650196 Mueller M. , "Leukotriene A4 hydrolase: protection from mechanism-based inactivation by mutation of tyrosine-378.'' Proc Natl Acad Sci U S A. 1996 Jun 11;93(12):5931-5.]</ref> | ||
+ | |- | ||
+ | |2.70E-03 | ||
+ | |mM | ||
+ | |Human | ||
+ | |Leukocytes, pH 8.0 at room temperature. | ||
+ | |<ref name="Stromberg1998"> [www.ncbi.nlm.nih.gov/pubmed/9744798 Stromberg F. , "Purification and characterization of leukotriene A4 hydrolase from Xenopus laevis oocytes.'' FEBS Lett. 1998 Aug 21;433(3):219-22.]</ref> | ||
+ | |- | ||
+ | |2.20E-02 | ||
+ | |rowspans=2|mM | ||
+ | |rowspans=2|Human | ||
+ | |2°C, pH 8.0 | ||
+ | |rowspans=2|<ref name="Radmark1984"> [www.ncbi.nlm.nih.gov/pubmed/6490615 Radmark O. , "Leukotriene A4 hydrolase in human leukocytes. Purification and properties'' J Biol Chem. 1984 Oct 25;259(20):12339-45.]</ref> | ||
+ | |- | ||
+ | |2.3E-03 | ||
+ | |37°C, pH 8.0 | ||
+ | |- | ||
|} | |} | ||
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! Reference | ! Reference | ||
|- | |- | ||
− | + | |12.6 - 28.2 | |
− | + | |per minute | |
+ | |Human | ||
+ | |Wild type enzyme, pH 7.4, 37 °C. | ||
+ | |<ref name="Rudberg2002"> [www.ncbi.nlm.nih.gov/pubmed/11675384 Rudberg P. , "Leukotriene A4 Hydrolase/Aminopeptidase'' The Journal of Biological Chemistry, 277, 1398-1404.]</ref> | ||
+ | |- | ||
+ | |51 | ||
+ | |per minute | ||
+ | |Human | ||
+ | |Wild Type, pH 8.0, at room temperature. | ||
+ | |<ref name="Mueller1996"> [www.ncbi.nlm.nih.gov/pubmed/8650196 Mueller M. , "Leukotriene A4 hydrolase: protection from mechanism-based inactivation by mutation of tyrosine-378.'' Proc Natl Acad Sci U S A. 1996 Jun 11;93(12):5931-5.]</ref> | ||
+ | |- | ||
+ | |90 | ||
+ | |per minute | ||
+ | |Human | ||
+ | |Leukocytes, pH 8.0 at room temperature. | ||
+ | |<ref name="Stromberg1998"> [www.ncbi.nlm.nih.gov/pubmed/9744798 Stromberg F. , "Purification and characterization of leukotriene A4 hydrolase from Xenopus laevis oocytes.'' FEBS Lett. 1998 Aug 21;433(3):219-22.]</ref> | ||
+ | |- | ||
+ | |125 | ||
+ | |per minute | ||
+ | |Human | ||
+ | |Leukcyte pH 8.0, 37 °C | ||
+ | |<ref name="Radmark1984"> [www.ncbi.nlm.nih.gov/pubmed/6490615 Radmark O. , "Leukotriene A4 hydrolase in human leukocytes. Purification and properties'' J Biol Chem. 1984 Oct 25;259(20):12339-45.]</ref> | ||
+ | |- | ||
|} | |} | ||
== Related Reactions == | == Related Reactions == |
Revision as of 14:46, 11 April 2016
Reaction
Chemical equation
Rate equation
Parameters
Value | Units | Species | Notes | Reference |
---|---|---|---|---|
5.80E-03 | mM | Human | Wild Type, pH 8.0, at room temperature. | [1] |
2.70E-03 | mM | Human | Leukocytes, pH 8.0 at room temperature. | [2] |
2.20E-02 | mM | Human | 2°C, pH 8.0 | [3] |
2.3E-03 | 37°C, pH 8.0 |
Value | Units | Species | Notes | Reference |
---|---|---|---|---|
12.6 - 28.2 | per minute | Human | Wild type enzyme, pH 7.4, 37 °C. | [4] |
51 | per minute | Human | Wild Type, pH 8.0, at room temperature. | [1] |
90 | per minute | Human | Leukocytes, pH 8.0 at room temperature. | [2] |
125 | per minute | Human | Leukcyte pH 8.0, 37 °C | [3] |
Related Reactions
- ↑ 1.0 1.1 [www.ncbi.nlm.nih.gov/pubmed/8650196 Mueller M. , "Leukotriene A4 hydrolase: protection from mechanism-based inactivation by mutation of tyrosine-378. Proc Natl Acad Sci U S A. 1996 Jun 11;93(12):5931-5.]
- ↑ 2.0 2.1 [www.ncbi.nlm.nih.gov/pubmed/9744798 Stromberg F. , "Purification and characterization of leukotriene A4 hydrolase from Xenopus laevis oocytes. FEBS Lett. 1998 Aug 21;433(3):219-22.]
- ↑ 3.0 3.1 [www.ncbi.nlm.nih.gov/pubmed/6490615 Radmark O. , "Leukotriene A4 hydrolase in human leukocytes. Purification and properties J Biol Chem. 1984 Oct 25;259(20):12339-45.]
- ↑ [www.ncbi.nlm.nih.gov/pubmed/11675384 Rudberg P. , "Leukotriene A4 Hydrolase/Aminopeptidase The Journal of Biological Chemistry, 277, 1398-1404.]