Difference between revisions of "Transformation of AA to 5-HPETE"

Revision as of 13:48, 8 April 2016

AA \rightleftharpoons PGH2

Michaelis-Menten Constants
Value	Units	Species	Notes	Reference
5.10E-03	$mM$	Human	Recombinant 5-Lipoxygenase	^[1]
1.20E-02	$mM$	Human	PMN Leukocyte	^[2]
6.31E-02	$mM$	Human	Polymorphonuclear Leukocytes	^[3]

Enzyme Turnover Numbers
Value	Units	Species	Notes	Reference

@@ Line 11: / Line 11: @@
-== Parameters ==
+== 5-LOX Parameters ==
@@ Line 23: / Line 23: @@
 ! Reference
 |-
+|5.10E-03
+|<math> mM </math>
+|Human
+|Recombinant 5-Lipoxygenase
+|<ref name="Shirumalla2006”>[http://www.ncbi.nlm.nih.gov/pubmed/17039282 Shirumalla R. K. “RBx 7,796: A novel inhibitor of 5-lipoxygenase.” Inflamm Res. 2006 Dec ; 55 (12) : 517-27.]</ref>
+|-
+|1.20E-02
+|<math> mM </math>
+|Human
+|PMN Leukocyte
+|<ref name="Soberman1988"> [http://www.ncbi.nlm.nih.gov/pubmed/3070300 Soberman R. J. "5- and 15(omega-6)-lipoxygenases from human polymorphonuclear leukocytes.'' Methods Enzymol. 1988; 163:344-9.]</ref>
+|-
+|6.31E-02
+|<math> mM </math>
+|Human
+|Polymorphonuclear Leukocytes
+|<ref name="Soberman1985”>[http://www.ncbi.nlm.nih.gov/pubmed/3920219 Soberman R. J. “Characterization and separation of the arachidonic acid 5-lipoxygenase and linoleic acid omega-6 lipoxygenase (arachidonic acid 15-lipoxygenase) of human polymorphonuclear leukocytes.” J Biol Chem. 1985 Apr 10;260(7):4508-15.]</ref>
+|-
 |}