Difference between revisions of "Transformation of AA to 12-HPETE"

Revision as of 13:56, 8 April 2016

AA \rightleftharpoons PGH2

Michaelis-Menten Constants
Value	Units	Species	Notes	Reference
7.20E-03	$mM$	Human	Platelet	^[1]
8.00E-02	$mM$	Human	Platelet	^[2]
1.00E-02	$mM$	Human	Recombinant Histidine-Tagged Human Platelet 12-Lipoxygenase	^[3]
7.90E-03 ± 8.00E-04	$mM$	Human	Platelet 12-Lipoxygenase	^[4]

Enzyme Turnover Numbers
Value	Units	Species	Notes	Reference

@@ Line 11: / Line 11: @@
-== Parameters ==
+== 12-LOX Parameters ==
 {|class="wikitable sortable"
@@ Line 22: / Line 22: @@
 ! Reference
 |-
+|7.20E-03
+|<math> mM </math>
+|Human
+|Platelet
+|<ref name="Lagarde1984"> [http://www.ncbi.nlm.nih.gov/pubmed/6433902 Lagarde M. "Subcellular localization and some properties of lipoxygenase activity in human blood platelets.'' Biochem J. 1984 Sep 1;222(2):495-500.]</ref>
+|-
+|8.00E-02
+|<math> mM </math>
+|Human
+|Platelet
+|<ref name="Hada1991"> [http://www.ncbi.nlm.nih.gov/pubmed/1851637 Hada T. "Catalytic properties of human platelet 12-lipoxygenase as compared with the enzymes of other origins.'' Biochim Biophys Acta. 1991 Apr 24;1083(1):89-93.]</ref>
+|-
+|1.00E-02
+|<math> mM </math>
+|Human
+|Recombinant Histidine-Tagged Human Platelet 12-Lipoxygenase
+|<ref name="Chen1993"> [http://www.ncbi.nlm.nih.gov/pubmed/8319693 Chen X. S. "Purification and characterization of recombinant histidine-tagged human platelet 12-lipoxygenase expressed in a baculovirus/insect cell system.'' Eur J Biochem. 1993 Jun 15;214(3):845-52.]</ref>
+|-
+|7.90E-03 ± 8.00E-04
+|<math> mM </math>
+|Human
+|Platelet 12-Lipoxygenase
+|<ref name="Romano1993"> [http://www.ncbi.nlm.nih.gov/pubmed/8250832 Romano M. "Lipoxin synthase activity of human platelet 12-lipoxygenase.'' Biochem J. 1993 Nov 15;296 ( Pt 1):127-33.]</ref>
+|-
 |}