Transformation of 5-HPETE to LTA4

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Reaction

R13 HPETE5-LTA4.jpg

Chemical equation

AA \rightleftharpoons PGH2

Rate equation

Parameters

Gibbs Free Energy Change
Value Units Species Notes Reference
(-86.007) kcal/mol Not stated Estimated

Enzyme: 15-LOX Substrate: 5-HPETE Product: LTA4 pH: 7.3 ionic strength: 0.25

[1]

Related Reactions

  1. ↑ Caspi et al 2014, "The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases," Nucleic Acids Research 42:D459-D471
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