Difference between revisions of "Transformation of 5-HPETE to LTA4"

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(Parameters)
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[[Welcome to the In-Silico Model of Cutaneous Lipids Wiki | Return to overview]]
 
[[Welcome to the In-Silico Model of Cutaneous Lipids Wiki | Return to overview]]
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The leukotriene products of the 5-LOX pathway, are important in the inflammation process as they are well-known for the recruitment of infiltrating inflammatory species such as neutrophils and leukocytes (Serhan, Jain et al. 2003, Sadik, Sezin et al. 2013).
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== Reaction ==
 
== Reaction ==
  

Revision as of 14:43, 31 August 2016

Return to overview

The leukotriene products of the 5-LOX pathway, are important in the inflammation process as they are well-known for the recruitment of infiltrating inflammatory species such as neutrophils and leukocytes (Serhan, Jain et al. 2003, Sadik, Sezin et al. 2013).

Reaction

R13 HPETE5-LTA4.jpg

Chemical equation

 AA \rightleftharpoons PGH2

Rate equation

Parameters

Gibbs Free Energy Change
Value Units Species Notes Reference
(-86.007) kcal/mol Not stated Estimated

Enzyme: 5-LOX Substrate: 5-HPETE Product: LTA4 pH: 7.3 ionic strength: 0.25

[1]

References

Related Reactions