Difference between revisions of "Transformation of 5-HPETE to 5-HETE"

Revision as of 11:11, 27 April 2016

AA \rightleftharpoons PGH2

Michaelis-Menten Constants
Value	Units	Species	Notes	Reference
3.00E-01	$mM$	Human	Bioimprited Enzyme	^[1]
11.1 ± 2.90E-01	$mM$	Human	Wild Type Enzyme (Se-hGSTZ1-1)	^[2]
4.00E-03	$mM$	Rat	Liver cytosol Se-GSH Px (5-HPETE as the substrate)	^[3]

Enzyme Turnover Numbers
Value	Units	Species	Notes	Reference
1170 ± 50	$min^{-1}$	Human	Bioimprited Enzyme	^[1]
24500 ± 150	$min^{-1}$	Human	Wild Type Enzyme (Se-hGSTZ1-1)	^[2]

Enzyme Concentrations
Value	Units	Species	Notes	Reference
0.0005-0.005	mM	Human	Bioimprited Enzyme	^[1]
0.004	mM	Human	Wild Type Enzyme (Se-hGSTZ1-1)	^[2]

@@ Line 63: / Line 63: @@
 |<ref name="Zheng2008"> [http://www.ncbi.nlm.nih.gov/pubmed/18373941 Zheng K. "A novel selenium-containing glutathione transferase zeta1-1, the activity of which surpasses the level of some native glutathione peroxidases.'' Int J Biochem Cell Biol. 2008;40(10):2090-7. doi: 10.1016/j.biocel.2008.02.006. Epub 2008 Feb 15.]</ref>
 |-
+|}
+{|class="wikitable sortable"
+|+  style="text-align: left;" | Enzyme Concentrations
+|-
+! Value
+! Units
+! Species
+! Notes
+! Reference
+|-
+|0.0005-0.005
+|mM
+|Human
+|Bioimprited Enzyme
+|<ref name="Liu2008"> [http://www.ncbi.nlm.nih.gov/pubmed/18163571 Liu L. "Functional mimicry of the active site of glutathione peroxidase by glutathione imprinted selenium-containing protein.'' Biomacromolecules. 2008 Jan;9(1):363-8. doi: 10.1021/bm7008312. Epub 2007 Dec 29.]</ref>
+|-
+|0.004
+|mM
+|Human
+|Wild Type Enzyme (Se-hGSTZ1-1)
+|<ref name="Zheng2008"> [http://www.ncbi.nlm.nih.gov/pubmed/18373941 Zheng K. "A novel selenium-containing glutathione transferase zeta1-1, the activity of which surpasses the level of some native glutathione peroxidases.'' Int J Biochem Cell Biol. 2008;40(10):2090-7. doi: 10.1016/j.biocel.2008.02.006. Epub 2008 Feb 15.]</ref>
 |}