Difference between revisions of "Transformation of 15-Keto-PGE2 to 13,14-Dihydro-15-Keto-PGE2"

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(Created page with " Return to overview Due to the lack of PGD2 production by keratinocyte and fibroblast cells, the anti-inflammator...")
 
(→‎Reaction)
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== Reaction ==
 
== Reaction ==
−
[[File:R8_PGD2_-_PGJ2.jpg|center|500px]]
 
  
 
==Chemical equation==
 
==Chemical equation==

Revision as of 15:12, 1 October 2016

Return to overview

Due to the lack of PGD2 production by keratinocyte and fibroblast cells, the anti-inflammatory cyclopentanones, PGJ2 and 15d-PGJ2, will not be produced during early experimental procedures either.


Reaction

Chemical equation

Failed to parse (Cannot store math image on filesystem.): 15-Keto-PGE2 \rightleftharpoons 13,14-Dihydro-15-Keto-PGE2

Rate equation

Parameters

Half Life
Value Units Species Notes Reference
9.9 +/-0.2 minutes Dog In vivo

Temperature:37 pH:7

[1]
  1. ↑ W. Bothwell, "A radioimmunoassay for the unstable pulmonary metabolites of prostaglandin E1 and E2: an indirect index of their in vivo disposition and pharmacokinetics" Journal of Pharmacology and Experimental Therapeutics February 1982, 220 (2) 229-235
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