Pyrophosphate phosphohydrolase

Pyrophosphate phosphohydrolase that catalyze the reaction that converts Pyrophosphate into two molecules of Phosphate.

Chemical equation

Failed to parse (Cannot store math image on filesystem.): PP \rightarrow 2 P

Rate equation

Simple Michaelis-Menten rate law is used for this reaction

$\frac{V_{max[PP]}}{[PP] + K_{m}^{PP}}$

Parameter values

• A mean body weight is defined as 75Kg in Konig et. al . The $V_{max}$ is calculated by multiplying the reported value with body weight.

Parameter	Value	Units	Organism	Remarks
$V_{max}$	$0.36$	$mM/min^{-1}$	Human Liver
Failed to parse (Cannot store math image on filesystem.): K_{m}^{PP}	Failed to parse (Cannot store math image on filesystem.): 0.0054	mM	Rat liver

Parameters with uncertainty

• The value of $V_{max}$ is reported to be $9.6 %$ of $V_{max, PGLM}$. The Std. Dev. for $V_{max, PGLM}$ was considered to be $10.5%$ of its mean value. Same error percentage is considered for $V_{max}$.

Parameter	Value	Units	Organism	Remarks
$V_{max}$	$0.36$	$mM/min^{-1}$	Human Liver
Failed to parse (Cannot store math image on filesystem.): K_{m}^{PP}	Failed to parse (Cannot store math image on filesystem.): 0.0054	mM	Rat liver