Difference between revisions of "Nucleosid diphosphate kinase"

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==Rate equation==
 
==Rate equation==
Rate is
+
Random order Bi-Bi rate law is used
 +
 
 +
<center><math></math>\frac{ \frac{V_{max}}{K_m^{ATP}K_m^{UDP}}\left( [ATP][UDP] - \frac{[ADP][UTP]}{K_{eq}}  \right)  }  {1}</center>

Revision as of 10:41, 13 May 2014

Nucleoside-diphosphate kinases are enzymes that catalyze the exchange of phosphate groups between different nucleotides. The overall effect of NDKs is to transfer a phosphate group from a nucleoside triphosphate to a nucleoside diphosphate. Starting with ATP and UDP, the activity of NDK produces ADP and UTP.

Chemical equation

ATP + UDP \leftrightarrow ADP + UTP

Rate equation

Random order Bi-Bi rate law is used

\frac{ \frac{V_{max}}{K_m^{ATP}K_m^{UDP}}\left( [ATP][UDP] - \frac{[ADP][UTP]}{K_{eq}} \right) } {1}