Difference between revisions of "Kinetic Model of Monoterpenoid Biosynthesis Wiki"
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== Strategies for Estimating Kinetic Parameter Values == | == Strategies for Estimating Kinetic Parameter Values == | ||
+ | |||
+ | === Calculating the Equilibrium Constant (K<sub>eq</sub>) === | ||
+ | |||
+ | Using the Haldane relationship, the equilibrium constant (K<sub>eq</sub>) can be written as: | ||
+ | |||
+ | :<math> | ||
+ | K_\mathrm{eq} = \frac{Vmax_\mathrm{forward} * Km_\mathrm{product} }{Vmax_\mathrm{reverse} * Km_\mathrm{substrate}} | ||
+ | </math> | ||
+ | |||
+ | Instead of using the ratio of the V<sub>max</sub> values, the reversible Michaelis-Menten rate equation were rewritten to contain the equilibrium constant. | ||
== Equilibrium Constant == | == Equilibrium Constant == | ||
== References == | == References == |
Revision as of 12:20, 19 February 2016
This wiki page describes the construction and simulation of a kinetic model of Monoterpenoid Biosynthesis.
Contents
Monoterpenoid Biosynthesis
Description of the model
Reversible Michaelis-Menten equation
All reactions in this model are described using reversible Michaelis-Menten equation.
Strategies for Estimating Kinetic Parameter Values
Calculating the Equilibrium Constant (Keq)
Using the Haldane relationship, the equilibrium constant (Keq) can be written as:
- Failed to parse (Cannot store math image on filesystem.): K_\mathrm{eq} = \frac{Vmax_\mathrm{forward} * Km_\mathrm{product} }{Vmax_\mathrm{reverse} * Km_\mathrm{substrate}}
Instead of using the ratio of the Vmax values, the reversible Michaelis-Menten rate equation were rewritten to contain the equilibrium constant.