Difference between revisions of "Degradation of R2"

From ISMOC
Jump to: navigation, search
(Parameters)
Line 27: Line 27:
 
|<math>0.000833-0.001667</math> <ref name="Trötschel2013"> Trötschel C, Albaum SP, Poetsch A. ''Proteome turnover in bacteria: current status for Corynebacterium glutamicum and related bacteria.'' Microbial biotechnology. 2013;6(6):708-719.</ref>  
 
|<math>0.000833-0.001667</math> <ref name="Trötschel2013"> Trötschel C, Albaum SP, Poetsch A. ''Proteome turnover in bacteria: current status for Corynebacterium glutamicum and related bacteria.'' Microbial biotechnology. 2013;6(6):708-719.</ref>  
 
| <math>min^{-1}</math>
 
| <math>min^{-1}</math>
| Degradation rates of protein in ''S. coelicolor''  
+
| Degradation rates of proteins in ''S. coelicolor''  
 
based on radioactive decay  
 
based on radioactive decay  
 
|  
 
|  

Revision as of 21:38, 28 September 2015

The ScbR homo-dimer (R2) degrades.

Go back to overview
About this image

Chemical equation

R_{2}\rightarrow \varnothing

Rate equation

 r= d_{R}\cdot[R_{2}]

Parameters

The parameter of this reaction is the degradation rate of R2 (d_{R}).

Name Value Units Origin Remarks
d_{R} 0.000833-0.001667 [1] min^{-1} Degradation rates of proteins in S. coelicolor

based on radioactive decay

Parameters with uncertainty

The most plausible parameter value for the d_{R} is decided to be  0.00118 min^{-1} and the confidence interval  1.41 . This means that the mode of the PDF is 0.00118 and the range where 95% of the values are found is between 0.000833 and 0.001667 min^{-1}.

The probability distribution for the parameter, adjusted accordingly in order to reflect the above values, is the following:

DR.png

The location and scale parameters of the distribution are:

Parameter μ σ
d_{R} -6.7120 0.174

References

  1. Trötschel C, Albaum SP, Poetsch A. Proteome turnover in bacteria: current status for Corynebacterium glutamicum and related bacteria. Microbial biotechnology. 2013;6(6):708-719.