Difference between revisions of "Decay of PGI2 to exPGI2"

From ISMOC
Jump to: navigation, search
(→‎Decay Parameters)
(→‎Decay Parameters)
 
Line 17: Line 17:
 
! style="text-align: center; font-weight: bold;" | Rate constant(min -1)
 
! style="text-align: center; font-weight: bold;" | Rate constant(min -1)
 
! style="text-align: center; font-weight: bold;" | Notes
 
! style="text-align: center; font-weight: bold;" | Notes
 +
! style="text-align: center; font-weight: bold;" | Weight
 
! style="text-align: center; font-weight: bold;" | Reference
 
! style="text-align: center; font-weight: bold;" | Reference
 
|-
 
|-
Line 24: Line 25:
 
| style="text-align: center;" | 0.231
 
| style="text-align: center;" | 0.231
 
| style="text-align: center;" |
 
| style="text-align: center;" |
 +
| style="text-align: center;" | 8
 
| style="text-align: center;" |<ref name="Cawello1994”>[https://www.ncbi.nlm.nih.gov/pubmed/8070511 Cawello W., "Metabolism and pharmacokinetics of prostaglandin E1 administered by intravenous infusion in human subjects." Eur J Clin Pharmacol. 1994;46(3):275-7.]</ref>
 
| style="text-align: center;" |<ref name="Cawello1994”>[https://www.ncbi.nlm.nih.gov/pubmed/8070511 Cawello W., "Metabolism and pharmacokinetics of prostaglandin E1 administered by intravenous infusion in human subjects." Eur J Clin Pharmacol. 1994;46(3):275-7.]</ref>
 
|-
 
|-

Latest revision as of 14:52, 22 May 2019

Return to overview

Return to Degradation Pathways


Rate equation

R48.PNG

Decay Parameters

Literature values
Reaction # Species Half Life (min) Rate constant(min -1) Notes Weight Reference
48 exPGI2 3 0.231 8 [1]
Description of the PGI2 decay constant distribution
Mode (min-1) Confidence Interval Location parameter (µ) Scale parameter (σ)
2.30E-01 1.10E+00 -1.46E+00 9.49E-02
The estimated probability distribution for PGI2 decay constant. The value and weight of the literature values used to define the distribution are indicated by an orange dashed line. The x axis is plotted on a log-scale.
The estimated probability distribution for exPGI2 decay constant. The value and weight of the literature values used to define the distribution are indicated by an orange dashed line. The x axis is plotted on a log-scale.

References

  1. ↑ Cawello W., "Metabolism and pharmacokinetics of prostaglandin E1 administered by intravenous infusion in human subjects." Eur J Clin Pharmacol. 1994;46(3):275-7.
Retrieved from ‘http://www.systemsbiology.ls.manchester.ac.uk/wiki/index.php?title=Decay_of_PGI2_to_exPGI2&oldid=7063’