Difference between revisions of "Decay of LTB4 to exLTB4"

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(→‎Decay Parameters)
(→‎Decay Parameters)
 
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! style="text-align: center; font-weight: bold;" | Rate constant(min -1)
 
! style="text-align: center; font-weight: bold;" | Rate constant(min -1)
 
! style="text-align: center; font-weight: bold;" | Notes
 
! style="text-align: center; font-weight: bold;" | Notes
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! style="text-align: center; font-weight: bold;" | Weights
 
! style="text-align: center; font-weight: bold;" | Reference
 
! style="text-align: center; font-weight: bold;" | Reference
 
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| style="text-align: center;" | 1.475 ± 34.657 to 1.100 ± 17.329
 
| style="text-align: center;" | 1.475 ± 34.657 to 1.100 ± 17.329
 
| style="text-align: center;" | Rabbit, Immunoreactive LTB4
 
| style="text-align: center;" | Rabbit, Immunoreactive LTB4
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| style="text-align: center;" | 8
 
| style="text-align: center;" | <ref name="Marleau1994”>[http://www.ncbi.nlm.nih.gov/pubmed/8075884 Marleau S., "Metabolic disposition of leukotriene B4 (LTB4) and oxidation-resistant analogues of LTB4 in conscious rabbits." Br J Pharmacol. 1994 Jun;112(2):654-8.]</ref>
 
| style="text-align: center;" | <ref name="Marleau1994”>[http://www.ncbi.nlm.nih.gov/pubmed/8075884 Marleau S., "Metabolic disposition of leukotriene B4 (LTB4) and oxidation-resistant analogues of LTB4 in conscious rabbits." Br J Pharmacol. 1994 Jun;112(2):654-8.]</ref>
 
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Latest revision as of 15:00, 22 May 2019

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Rate equation

R56.PNG

Decay Parameters

Literature values
Reaction # Species Half Life (min) Rate constant(min -1) Notes Weights Reference
56 exLTB4 0.47 ± 0.02 to 0.63 ± 0.04 1.475 ± 34.657 to 1.100 ± 17.329 Rabbit, Immunoreactive LTB4 8 [1]
Description of the LTB4 decay constant distribution
Mode (min-1) Confidence Interval Location parameter (µ) Scale parameter (σ)
1.47E+00 1.10E+00 3.93E-01 9.49E-02
The estimated probability distribution for LTB4 decay constant. The value and weight of the literature values used to define the distribution are indicated by an orange dashed line. The x axis is plotted on a log-scale.
The estimated probability distribution for exLTB4 decay constant. The value and weight of the literature values used to define the distribution are indicated by an orange dashed line. The x axis is plotted on a log-scale.

References

  1. ↑ Marleau S., "Metabolic disposition of leukotriene B4 (LTB4) and oxidation-resistant analogues of LTB4 in conscious rabbits." Br J Pharmacol. 1994 Jun;112(2):654-8.
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