DXS

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The DXS reaction (EC 2.2.1.7)


Pyruvate + G3P \rightleftharpoons DXP + CO2

Deoxyxylulose-5-phosphate synthase (DXS) catalyses the production of 1-deoxy-D-xylulose 5-phosphate (DXP) from pyruvate and glyceraldehyde 3-phosphate (G3P). This reaction is the first step in the MEP pathway.

Modelling DXS

In the kinetic model, the DXS reaction is modelled with reversible Michaelis-Menten using the Hanekom [1] bi-bi random order generic equation.



References

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Enzyme and Metabolite Background Information

  1. Hanekom2016