Difference between revisions of "Acetoacetyl transferase (AACT)"
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| + | You can go back to main page of the kinetic model [http://www.systemsbiology.ls.manchester.ac.uk/wiki/index.php/Kinetic_Model_of_Monoterpenoid_Biosynthesis_Wiki '''here''']. | ||
| + | |||
| + | Acetoacetyl transferase (AACT, EC 2.3.1.9 ) is the first step in the MVA pathway. In the model, AACT is local to ''E. coli''. | ||
| + | |||
| + | :<math> | ||
| + | |||
| + | 2 AcetylCoA \rightleftharpoons AcetoacetylCoA + coA | ||
| + | |||
| + | </math> | ||
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| + | |||
= AACT Parameter Values = | = AACT Parameter Values = | ||
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|+ Keq values for AACT | |+ Keq values for AACT | ||
! Value | ! Value | ||
| − | ! | + | ! ΔG°' (kcal/mol) |
! Literature | ! Literature | ||
! Reference | ! Reference | ||
|- | |- | ||
| − | | 1 ± 0.5 E-02 | + | | style="width: 5%;" |1 ± 0.5 E-02 |
| − | | | + | | style="width: 5%;" | |
| − | | | + | | style="width: 20%;" |[[File:Lan_2012_AACT.png|450px|Keq value for AACT]] |
| − | | <ref name=Lan2012>Lan, E. I. and J. C. Liao (2012). "ATP drives direct photosynthetic production of 1-butanol in cyanobacteria." PNAS 109(16): 6018-6023.</ref> | + | | style="width: 5%;" |<ref name=Lan2012>Lan, E. I. and J. C. Liao (2012). "ATP drives direct photosynthetic production of 1-butanol in cyanobacteria." PNAS 109(16): 6018-6023.</ref> |
|- | |- | ||
| 6.63E-06 | | 6.63E-06 | ||
| − | | 7.06 | + | | 7.06 |
| − | | | + | | [[File:Metacyc_AACT.png|450px|Keq value for AACT]] |
| <ref name=MetaCycAACT> MetaCyc </ref> | | <ref name=MetaCycAACT> MetaCyc </ref> | ||
|- | |- | ||
| 1.1 ± 0.2 E-05 | | 1.1 ± 0.2 E-05 | ||
| − | | | + | | 6.8 |
| − | | | + | | [[File:Gilbert_1981_AACT.png|450px|Keq value for AACT]] |
| <ref name=Gilbert1981>Gilbert, H. F., et al. (1981). "The relation of acyl transfer to the overall reaction of thiolase I from porcine heart." The Journal of Biological Chemistry </ref> | | <ref name=Gilbert1981>Gilbert, H. F., et al. (1981). "The relation of acyl transfer to the overall reaction of thiolase I from porcine heart." The Journal of Biological Chemistry </ref> | ||
|} | |} | ||
Latest revision as of 14:05, 18 June 2019
You can go back to main page of the kinetic model here.
Acetoacetyl transferase (AACT, EC 2.3.1.9 ) is the first step in the MVA pathway. In the model, AACT is local to E. coli.
AACT Parameter Values
| Value | ΔG°' (kcal/mol) | Literature | Reference |
|---|---|---|---|
| 1 ± 0.5 E-02 | 
|
[1] | |
| 6.63E-06 | 7.06 | 
|
[2] |
| 1.1 ± 0.2 E-05 | 6.8 | 
|
[3] |
AACT Parameter Distribution Properties
References
- ↑ Lan, E. I. and J. C. Liao (2012). "ATP drives direct photosynthetic production of 1-butanol in cyanobacteria." PNAS 109(16): 6018-6023.
- ↑ MetaCyc
- ↑ Gilbert, H. F., et al. (1981). "The relation of acyl transfer to the overall reaction of thiolase I from porcine heart." The Journal of Biological Chemistry
