Glycine hydroxymethyltransferase

Glycine hydroxymethyltransferase catalyzes the chemical reaction that converts Serine to Glycine.

Reaction equation

Serine \rightleftharpoons Glycine

A modified rate law is used to determine the velocity of this reaction.

v = \frac{serD*KcatD* \frac{[Serine]}{KD_{Serine}} }{ 1 + \frac{[Serine]}{KD_{Serine}} + \frac{[Glycine]}{KD_{Glycine}} }

Parameter	Value	Units	Organism
$serD$	0.115 ^[1]	mM	Escherichia coli
$KcatD$	1.83 ^[1]	1/s
Failed to parse (Cannot store math image on filesystem.): KD_{Serine}	0.8^[1]	mM
Failed to parse (Cannot store math image on filesystem.): KD_{Glycine}	1 ^[1]	mM

↑ ^1.0 ^1.1 ^1.2 ^1.3 Turnaev II, Ibragimova SS, Usuda Y et al (2006). Mathematical modeling of serine and glycine synthesis regulation in Escherichia coli. Proceedings of the fifth international conference on bioinformatics of genome regulation and structure 2:78–83