UDPG-pyrophosphorylase
This enzyme converts UTP and G1P to UDP-glucose (UDPG) and pyrophosphate (PPi)
Chemical equation
Rate equation
Reversible Bi substrate Michaelis-Menten equation with random binding order is used [1]
Parameter values
Parameter | Value | Organism | Remarks |
---|---|---|---|
200 [2] | HeLa cell line | Recombinant, human muscle | |
0.4 [3] | Recombinant, human muscle | ||
0.92 [3] | Recombinant, human muscle | ||
[3] | Recombinant, human muscle | ||
[3] | Recombinant, human muscle | ||
0.24 <ref name="bergamini_1983">Bergamini C, Signorini M, Ferrari C & Dallocchio F (1983) Non-Michaelian kinetics of rabbit muscle uridine diphosphoglucose pyrophosphorylase. ArchBiochem Biophys 227, 397–405. |
References
- ↑ Palm, D.C. (2013). The regulatory design of glycogen metabolism in mammalian skeletal muscle (Ph.D.). University of Stellenbosch
- ↑ Villar-Palasi C & Larner J (1960). Levels of activity of the enzymes of the glycogen cycle in rat tissues. Arch Biochem Biophys 86, 270–273.
- ↑ 3.0 3.1 3.2 3.3 Duggleby RG, Chao YC, Huang JG, Peng HL & Chang HY (1996). Sequence differences between human muscle and liver cDNAs for UDPglucose pyrophosphorylase and kinetic properties of the recombinant enzymes expressed in Escherichia coli. Eur J Biochem 235, 173–179.