Dehydrogenase

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A dehydrogenase is an enzyme that oxidizes a substrate by a reduction reaction that transfers one or more hydrides (H) to an electron acceptor, usually Nicotinamide adenine dinucleotide NAD+/NADP.

Chemical reaction

 NADH \rightleftharpoons NAD

Rate equation

Reversible mass action rate law is used

K_{1}[NADH] - K_{2}[NAD]

Parameters

Parameter Value Organism Remarks
K_{1} 250 [1] HeLa cell line
K_{2} 1[1]

References

  1. 1.0 1.1 Marín-Hernández A, Gallardo-Pérez JC, Rodríguez-Enríquez S et al (2011) Modeling cancer glycolysis. Biochim Biophys Acta 1807:755–767 (doi)