Equilibrium Constant Calculations
The Haldane Equation
Keq = exp (-Gibbs/RT)
Negative: Spontaneous Reaction Zero: Equilibrium Positive: Not spontaeous
Quantifying the Uncertainty of Gibbs Free Energies
| Gibbs Free Energy | ||||
|---|---|---|---|---|
| Enzyme | Weighted
Mode |
Confidence
Interval |
Location
Parameter |
Scale
Parameter |
| 12-LOX | -69.98 | 10 | ||
| 15-LOX | -69.98 | 10 | ||
| 5-LOX | -69.98 | 10 | ||
| 5-LOX/FLAP | -86.01 | 10 | ||
| COX-1/-2 | -39.00 | 10 | ||
| cPLA2 | -13.04 | 10 | ||
| LTA4H | -3.63 | 10 | ||
| LTC4S | 9.93 | 10 | ||
| PGDS | -6.64 | 10 | ||
| PGES | -6.64 | 10 | ||
| PGFS | -6.64 | 10 | ||
| PGIS | 0.04 | 10 | ||
| PHGPx | -26.94 | 10 | ||
| TXAS | 41.08 | 10 | ||
