Phosphoglucomutase
Phosphoglucomutase (PGLM) facilitates the interconversion of glucose 1-phosphate and glucose 6-phosphate by transfering a phosphate group on an α-D-glucose monomer from the 1' to the 6' position in the forward direction or the 6' to the 1' position in the reverse direction.
Chemical reaction
![Glc6P \rightleftharpoons Glc1P](/wiki/images/math/7/0/4/7040d3c0b100087ac04f564636bf046c.png)
Rate equation
Mono substrate reversible Michelis-Menten with Haldane substitution is used as a rate law. [1]
![\frac{\frac{V_{max}}{K_{Glc6P}}\left( [Glc6P] - \frac{[Glc1P]}{K_{eq}} \right) }{1 + \frac{[Glc6P]}{K_{Glc6P}} + \frac{[Glc1P]}{K_{Glc1P}} }](/wiki/images/math/b/3/b/b3b31230b8a8021f39eedd96660f53ae.png)
Parameter values
References
- ↑ Palm, D.C. (2013). The regulatory design of glycogen metabolism in mammalian skeletal muscle (Ph.D.). University of Stellenbosch